Saurastra University 2006 M.B.B.S Pathology (Theory) - Question Paper
Z-4664 Seat No._
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Second Year M.B.B.S. Examination February - 2006 Pathology (Theory)
[Total Marks : 80Time : 3 Hours] Instructions
(1) Figures to the right indicate full marks.
(2) Write answers of Paper-I and Paper-II in separate answer books.
(3) Draw neat and labelled diagrams and write to the point.
(4) Irrelevant writing is diacourvaged.
PAPER -1
1 Write notes on : (any four) 20
(a) Biochemical themes / molecular mechanisms for cell injury and cell-death.
(b) Free radical cell-injury / super oxide.
(c) Transplant rejection-morphology and mechanisms.
(d) Chemical carcinogenesis-Discuss in detail.
(e) Physical and chemical nature of amyloid and classification of amyloidosis in detail.
2 (a) Answer in brief (objective) : (any three)
6
(a) Deficiency states / targets of Thiamine deficiency.
(b) Four organs with lesions involved in chronic alcoholism.
(c) Two examples EACH of Auto-immune diseases in single organ / cell type and systemic.
(d) Four examples of Prolonged Prothrombin time.
(b) Write brief answers : (any three)
6
(a) Define Leukaemia reaction, classify and mention causes of EACH.
(b) Inclusions of nuclear chromatin in red blood cells-Discuss.
(c) Reticulocyte-Morphology, staining, Method of count and mention four conditions of Reticulocytosis.
(d) Define anaemia. Classify and enumerate basic, routine and specialized investigations for anaemia.
[ Contd.
3 Write notes (any two) 8
(a) Morphology of premature WBC series cells individually and classify Leukemias.
(b) Discuss screening tests in evaluation of haemorhagic disorders and ONLY name some specific tests in detection of specific defects / disorders.
(c) Classify Macrocytic anaemia and discuss Lab. diagnosis of Macrocytic anaemias.
4 Write notes on : 12
(a) Discuss autopsy findings, external and internal examination and its clinico-pathological correlation in a patient died of AIDS.
(b) Define Rheumatic fever, discuss incidence, etiopathogenesis, morphology and clinical course of Rheumatic heart disease.
5 Write notes : (any four) 16
(a) Classify emphysema. Discuss the incidence, pathogenesis and morphology in detail.
(b) Classify Hepatitis viruses. Discuss the morphology, clinical details and serologic markers of hepatitis - c -virus infection in detail.
(c) Tubulo-interstitial diseases - Enumerate causes, discuss etiopathogenesis and morphology of Acute and Chronic Pyelonephritis.
(d) Define Infarct. Discuss the types, morphology, factors affecting development of infarct and clinical course in detail.
(e) Discuss regulation of normal blood pressure. Write down the mechanisms of Essential hypertension and vascular pathology in hypertension.
6 (a) Write in brief : (any three) 6
(a) Discuss Anisopoikilocytosis. Give some examples of variables of shapes and sizes.
(b) ESR - mention various methods, mechanisms and enumerate causes of increased and decreased ESR.
(c) Autoagglutination - causes and methods for evaluation of blood group in such condition.
(d) Liver function tests - Indications, various tests and its clinicopathological correlation / significance.
(b) Write short notes : (any two) 6
(a) Renal function tests - Indications, various tests, methods and clinicopathological significance.
(b) Investigations of a case of mismatched blood transfusion.
(c) Thyroid function tests - indications, clinicopathological correlation, utility and its significance.
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