Alagappa University 2007 M.Phil RESEARCH METHODOLOGY - Question Paper

Time : 3 hours Maximum : 100 marks
ans any 5 ques..
All ques. carry equal marks.
1. State the principle of microscopy and its applications in biology. discuss in detail about phase contrast and interference microscopy in cytological studies.
2. provide an account of the basic principles and applications of kinds of chromatography. discuss HPLC and its advantages.
3. define in detail the isolation and amplification of DNA from prokaryotes.
4. Write notes on:
(a) Polymerase chain reaction
(b) DNA fingerprinting
(c) Biolistics.
5. With suitable example discuss the histochemical expression of ‘‘gus’’ gene in transformed callus cultures and intact plants.
6. With illustrations discuss analysis of variance and correlation regression for statistical reduction of scientific datas.
7. Explain:
(a) Dynamic programming algorithms
(b) Pharmacogenomics
(c) Protein structure prediction.
8. explain in detail about tree searching and discuss the concept of indexed sequential searching.

Earning:   Approval pending.