Acharya Nagarjuna University (ANU) 2007 B.Pharm PHARMACEUTICAL BIOTECHNOLOGY - Question Paper

III/IV B.pharm. DEGREE EXAMINATION,
APRIL/MAY 2007.

(Examination at the end of 3rd Year of
four Year Course)

(Regular)

PAPER IV- PHARMACEUTICAL BIOTECHNOLOGY

TIME-3 HOURS MAXIMUM: 80 Marks

ans any 5 ques..

ALL ques. CARRY EQUAL MARKS

1. define the methods used to screen micro organisms for producing
bio active components. [16]

2. elaborate the main parameters to be controlled in a fermentation
process? define how those are controlled by various parts in a
fermentor. [16]

3. Desribe the fermentative production of the subsequent :

a) Citric acid.

b) Alcohol. [8+8]

4. discuss the importance of sterlity testing. define the methods
of sterlity testing.Add a note on sampling techniques. [4+8+4]

5. Write the principle and procedure for the microbiological assay of:

a) Vitamin B12.

b) Streptomycin. [8+8]

6. a) discuss the term 'Enzyme Immobilation 'What are to advantages and
and limitations.

b) define the various kinds of reactions occuring in microbial
transformations. [8+8]

7. What do you understand by the term 'Recombinant DNA technology '.
define the production of insulin by R-DNA technology. [4+12]

8. Write short notes on any 4 of the subsequent :

a) Antitoxins.

b) Heparin.

c) Monoclonal antibodies.

d) Dextran.

e) Streptokinase.

f) Principle of Radio-Immuno Assay

testing

Earning:   Approval pending.