Acharya Nagarjuna University (ANU) 2005 M.Sc Microbiology VII - MICROBIAL GENETICS AND MOLECULAR BIOLOGY - exam paper

M.Sc. (Final) DEGREE EXAMINATION, DECEMBER 2005.
Second Year
Microbiology
Paper VII - MICROBIAL GENETICS AND MOLECULAR BIOLOGY

Time : 3 hours Maximum : 100 marks

PART A - (5 x eight = 40 marks)
ans any 5 of the subsequent.
All ques. carry equal marks.

1. Ti plasmid and its uses.
2. Conjugational gene mapping in bacteria.
3. DNA mutations.
4. Rolling circle meachanism of replication.
5. Positive and Negative control of gene.
6. Translation in eukaryotes.
7. Cosmids.
8. PCR.

PART B - (4 x 15 = 60 marks)
ans all the 4 ques..
All ques. carry equal marks.

9. (a) define various theories of gene concept.

Or

(b) define the genetic recombination in phage and how is T4 genome mapped.

10. (a) Compare the enzymatic machinery and mechansim of DNA replication in prokaryotes to that of eukaryotes.

Or

(b) define the mechanisms of different DNA lesions and their repair in bacteria.

11. (a) define in detail the genetics of Nitrogen fixation and its regulation in Rhizobium

Or

(b) define different RNA components that are involved during transcription and translation in prokaryotes.

12. (a) define the structural organization and mechanism for movement of transposans.

Or

(b) define different methods that generate transgenic plants and animals with suitable
examples.

Earning:   Approval pending.