Exam paper-Sardar Krushinagar Dantiwada Agricultural Uiversity 2010 Bachelor of Veterinary Science & Animal-Husbandary for competitive

MULTIPLE CHOICE QUESTION

VETERINARY SCIENCE & ANIMAL HUSBANDRY

(For Competitive Examination of Veterinary Science)

Blood returning from the lungs enters the heart through the:
a. pulmonary semilunar valve
b. mitral valve
c. right ventricle
d. left atrium

The precursor of ketone body is

a. Acetyl CoA

b.Acetoacetic acid

c. Betahydroxybutyric acid

d. Cholesterol

For intravenous (IV) dosages, what is the bioavailability assumed to be?

a) 0%

b) 25%

c) 75%

d) 100%

Which of the following is NOT a pharmacokinetic process?

a)                                           Alteration of the drug by liver enzymes

b)                                          Drug metabolites are removed in the urine

c)                                           Movement of drug from the gut into general circulation

d)                                          The drug causes dilation of coronary vessels

Which of the following has no side effects?

a)                                           Paracetamol

b)                                          Aspirin

c)                                           Meloxicam

d)                                          None of above

Most drugs are either ____ acids or ____ bases.

a) Strong; Strong

b) Strong; Weak

c) Weak; Weak

d) All of above

Which of the following enteral administration routes has the largest first-pass effect?

a) SL (sublingual)

b) Buccal

c) Rectal

d) Oral

Which of the following would receive drug slowly?

a) Liver

b) Brain

c) Fat

d) Muscle

Pharmacokinetics is the effect of the ____ and Pharmacodynamics is the effect of the ____.

a)  Drug on a drug; Body on the drug

b) Body on the drug; Drug on a drug

c)  Drug on the body; Body on the drug

d) Body on the drug; Drug on the body

Which of the following is NOT an action of the body on a drug?

a)  Absorption

b) Distribution

c)  Metabolism

d) Side effects

Which of the following is the amount of a drug absorbed per amount administered?

a) Bioavailability

b) Bioequivalence

c) Drug absorption

d) All of above

What type of drugs can cross the blood-brain barrier (BBB)?

a) Large and lipid-soluble

b) Large and lipid-insoluble

c) Small and lipid-soluble

d) Small and lipid-insoluble

Which of the following is NOT a phase II substrate?

a) Glucuronic acid

b) Sulfuric acid

c) Acetic acid

d) Amino acids

Which of the following reactions is phase II and NOT phase I?

a)      Oxidations

b)      Reductions

c)      Conjugations

d)     Deaminations

What is the goal of the Cytochrome-P450 system?

a)      Metabolism of substances

b)      Detoxification of substances

c)      Decreasing pH of compartments containing substances

d)     A & B

Weak acids are excreted faster in ____ urine and weak bases are excreted faster in____ urine.

a)      Acidic; Alkaline

b)      Alkaline; Acidic

c)      Acidic; Neutral

d)     Alkaline; Neutral

Which organ is responsible for metabolism in the first pass effect?

a)      Brain

b)      Heart

c)      Kidney

d)     Liver

What determines the degree of movement of a drug between body compartments?

a)      Partition constant

b)      Degree of ionization

c)      Size

d)     All of the above

Following is responsible for agglutination of RBC in animal body.

a) Abrin

b) Ricin

c) Renin

d) Thiamine

Bovine Bunker is synonym to

a) Urea toxicity

b) Salt toxicity

c) Oxalates toxicity

d) Selenium toxicity