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M.Sc-M.Sc BioTechnology 1st Sem BT - 12 : Molecular and Cell Biology(University of Pune, Pune-2013)

Friday, 28 November 2014 01:55Nitha

                                  M.Sc. (Semester - I)


SEAT No. :

[Total No. of Pages : 2


BIOTECHNOLOGY

BT - 12 : Molecular and Cell Biology

(2008 Pattern)

Time : 3 Hours]                                                                                            [Max. Marks :80

Instructions to the candidates :

1) Attempt not more than 5 questions of which at least 2 questions must be from

each section.

2) Answers to the two sections should be written in separate books. 3) Neat diagrams must be drawn wherever necessary. 4) Figures to the right indicate full marks. 5) All questions carry equal marks.

SECTION - I

Q1) a)      Enlist the major differences between oxidative phosphorylation and photo

phosphorylation.                                                                                            [8]

b)       What are the major features of F1 F0 ATPase complex?                  [8]

Q2) a)      Describe in detail the modulation of cytosolic Ca++.                          [8]


b)Highlight the role of inositol - 1, 4, 5 triphosphate in Ca ++ signaling pathway.[8]


Q3) a)      Describe the external respiration.                                                             [8]

b)       What are the factors on which efficient external respiration depends upon?[8]

Q4) a)      Describe the physiological and metabolic effects of epinephrine.           [8]

b)       How does skin contributes to the regulation of body temperature? [8]

SECTION - II

Q5) a)      What do you understand by differential gene expression?              [8]

b)       How does the environmental factors influence expression of gene? [8]

Q6) a)      What are interferons? Describe the cellular process involved in Innate

defense mechanism.                                                                                       [8] b)   Describe natural defense against diseases in animals.                                                   [8]

P.T.O.


Q7) a)      What is the role of gene promoter like TATA boxes?                      [8]

b)       How does the “machinery” of the cell know where to begin reading the

gene.                                                                                                                      [8]

Q8) a)      “Ribosomes are the work benches for translation”. Justify the statement.[8]

b)       Describe the role of genetic variation and natural selection in evolution.[8] 


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