M.Sc-M.Sc Bio Chemistry 3rd Sem BCH - 372 : Neurochemistry(University of Pune, Pune-2013)
M.Sc. (Semester - III)
BIOCHEMISTRY
SEAT No. :
[Total No. of Pages : 2
BCH - 372 : Neurochemistry
(2010 Pattern)
Time : 3 Hours] [Max. Marks : 80
Instructions to the candidates:
1) All questions are compulsory.
2) Figures to the right indicate full marks.
3) Draw necessary diagrams wherever necessary.
Q1) Answer any four of the following:
Describe the ionic basis for inhibitory and excitatory post-synaptic
potentials and how these changes can alter synaptic transmission.
Compare conduction velocities in a compound nerve, identifying how
the diameter and myelination lead to differences in conduction velocity, and the use of these differences to classify neurons.
Describe the anatomy and functions of the major ascending and
descending spinal cord tracts, including any crossing of midline.
Differentiate Chemically Gated and Voltage-Gated Channels? What are the characteristics of a neurotransmitter.
Q2) Attempt any two of the following : [20]
Describe the overall function of the basal ganglia in movement control
and initiation in association with medial and lateral motor systems.
Describe ionic basis of an action potential.
Explain the mechanisms proposed for short term and long-term memory
storage.
P.T.O.
Q3) Answer any two of the following : [20]
Draw a cross section of the spinal cord and discuss the organization of the sensory and motor components of gray matter.
Describe the somatotropic arrangement of motor neuron pools.
Explain the effects of demyelination on action potential propagation and nerve conduction.
Describe the synthetic pathways, inactivation mechanisms and neurochemical anatomy and mechanisms of receptor transduction for the following neurotransmitters:
i) Serotonin ii) Histamine
Q4) Write short notes on any four : [20]
Basilar membrane. Synaptic plasticity.
Memory processing.
Rod and cone cells.
Sensory circuits.
TTT
| Earning: Approval pending. |
