M.Pharm-M.Pharm 1st Year MEDICINAL BIOCHEMISTRY(Kerala University of Health Sciences-2013)

QP CODE: 103326 Reg. No:...................... .
First Year Pharm D Degree Supplementary Examinations - March 2013
MEDICINAL BIOCHEMISTRY

Time: 3 Hours                                                                                              Total Marks: 100

• Answer all questions

• Write equations, draw diagrams wherever necessary

Essay: (2x10=20)

1. Describe the metabolism of purine and pyrimidine nucleotides in detail.
2. List various biochemical roles carried out by kidney. Outline methods to assess kidney dysfunction.
Short Notes: (10x3=30)
3. Explain isoenzymes as diagnostic tools
4. Formation of ketone bodies
5. Explain the role of liver in metabolism
6. Co-enzymes and their signif icance
7. Liver function tests
8. DNA repair mechanism
9. Hormonal regulation of carbohydrate metabolism
10. Enlist the immunochemical techniques for determinatio n of hormones
11.Metabolic disorders of amino acids
12.Gluconeogenesis and its significance
Answer briefly: (10x2=20)
13.Renal calculi
14.Glycogen storage diseases
15.Energy rich compounds
16.Hyperurobilinogen
17.Triglycerides and their significance
18.Dye test for excretory function
19.Genetic code
20. β-oxidation
21. Proteinuria
22.Biochemical role of nucleotides
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