M.Pharm-M.Pharm 4th Year Biostatistics & Research Methodology(Kerala University of Health Sciences-2014)

Q.P. Code: 404326 Reg. no.: …………………
Fourth Year Pharm D Degree Examinations, August 2014
Biostatistics & Research Methodology

Time: 3 Hours                                                                                                      Total Marks: 70

• Answer all questions

• Draw diagrams wherever necessary

Essay: (3x10=30)

1. Classify the various types of clinical study designs. Explain case and observational studies with suitable examples.

2. Explain the advantages and disadvantages of non - parametric tests. Enumerate the various non-parametric tests. Add a note on Wilcoxan’s signed rank test.

3. Define testing hypothesis. Outline the different stages involved in testing of a hypothesis.

Short notes: (8x5=40)

4. Estimate mean, standard deviation for the hemoglobin values (gm/dl) of 10 children receiving therapy for haemolytic anemia.

8.3 9.1 10.0 9.9 11.3 12.3 9.13 9.8 7.5 and 6.6

5. Explain different statistical softwares.

6. Semi-logarthimic plots.

7. Computerized literature retrieval.

8. Type-I and type-II errors.

9. Paired and unpaired t-tests.

10.One way Anova

11. Relative and attributable risks.

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Earning:   Approval pending.