B.Pharm-B.Pharm 4th Year PHARMACEUTICAL ANALYSIS - II(Kerala University of Health Sciences-2014)

QP CODE:402006                                      Reg.No: ……………………..
Final Year B.Pharm Degree Examinations - September 2014
PHARMACEUTICAL ANALYSIS - II

Time: 3 Hours                                                                                                                      Total Marks: 100

• Answer all Questions.

• Draw diagrams and equations wherever necessary.

Essay (3x10=30)

1. Explain the principle of potentiometric titration and describe the applications of the
same.
2. Discuss the principle of separation in gas chromatography and detectrors used in GC
3. Explain the principle involved in fluorimetry. Describe the instrumentation of a
fluorimeter
Short notes (14x5=70)
4. Explain the different methods of preparing a TLC plates.
5. Explain the different developmental techniques used in paper chromatography
6. Differentiate column chromatography and HPLC.
7. Theory of light scattering and pharmaceutical applications of nephelometry
8. Different types of conductometric titrations
9. Applications of thermal analysis
10. Applications of infra red spectroscopy
11. Theory behind polarographic analysis
12. Define Beer’s Lambert law and explain its application in UV-visible spectroscopy
13. What are the different types of vibrations shown by a molecule when irradiated by
Infra red radiation.
14. Explain the theory of NMR in brief.
15. Explain the various types of burners used in flame photometry
16. Explain the instrumentation of electrophoresis.
17. Explain the salient features of good laboratory practice (GLP)
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