B.Pharm-B.Pharm 2nd Year Physical Pharmacy (Kerala University of Health Sciences-2014)

Monday, 27 October 2014 10:26Nitha

QP CODE:203008 Reg.No: ……………………..

Second B.Pharm (Ayurveda) Degree Supplementary Examinations,
April 2014
Physical Pharmacy

Time: 3 Hours Total Marks: 100

• Answer all questions.

Essays: (2x10=20)

1. Define adsorption isotherm. Draw various types of absorption isotherms and explain its behavior

2. Discuss the factors influencing physical stability of suspensions

Answer briefly: (10x5=50)

3. Factors influencing the dissolution of drugs

4. Fick’s first law

5. Formation of electrical double layer with a neat labeled diagram

6. Working principle of Coulter- Counter with diagram

7. Describe the process of micellar solubilization and its applications in pharmacy

8. Rheological behavior of suspensions

9. Causes for the instability of emulsions

10. Draw the flow curves for Newtonian and non-Newtonian types of flow. Mention one example for each type of flow

11. Factors influencing rate of reaction

12. Two methods for the purification of colloids

Short notes: ( 10x3=30)

13. State Henrys’ law for the solubility of gases in liquid

14. Define emulsion. Mention two advantages of emulsions with suitable examples

15. Role of polymers and surfactants in the formulation suspension

16. Two methods of mechanical dispersion for preparing lyophobic colloids

17. Plug flow and yield value

18. Define porosity. What is its applications in pharmacy

19. Concept of surface tension

20. Concept of half life in first order reaction

21. Mention the Hixson-Crowell cube root law and explain the terms. What is its importance in pharmacy

22. Define contact angle and mention its applications.

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