M.B.B.S-M.B.B.S 2nd Year Pharmacology- Paper II (Kerala University of Health Sciences-2014)

Q.P. Code: 202001                                                              Reg. no.: …………………
                    Second Professional MBBS Degree Supplementary Examinations,
                                                          September 2014
                                                        Pharmacology- Paper II

Time: 2 Hours                                                                                           Total Marks: 40
• Answer all questions
• Draw diagrams wherever necessary

 

Essays: (2x6=12)

1. Classification of fluoroquinolones .Describe the mechanism of action, therapeutic uses and
adverse effects of sparfloxacin. (2 + 2+ 2 =6)

 

2. Read the case history and answer the following questions. Mr. Raman 32 years has
developed severe epigastric pain after taking tab. Ibuprofen 400mg tds for his joint pain
• Mention two drugs used in NSAID induced gastric ulceration
• Mechanism of action of proton pump inhibitors
• Drugs for eradication of H.pylori infection

Short notes: (5x3=15)

3. Bisphosphonates

4. Adverse effects of aminoglycosides

5. Anti thyroid drugs

6. Rifampicin.

7. Taxanes in cancer chemotherapy.

 

Answer briefly: (5x1=5)

8. Two uses and two adverse effects of oral contraceptive pills

9. Mechanism of action of metoclopramide

10. Two advantages of human insulin

11. Specify the important spectrum of vancomycin

12. Rationale of estrogen in hormone replacement therapy

 

Name two drugs: (8x1=8)

13. Chloroquine resistant malaria.

14. Urinary tract infections

15. Immunosuppressive in organ transplantation

16. Irritable bowel syndrome.

17. Gram negative septicemia

18. Tocolytics

19. Aromatase inhibitors

20. Retro viral infections
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Earning:  ₹ 7.10/-