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B.Sc-B.Sc Chemistry 1st Sem (West Bengal Institute of Technology (WBIT), Kolkata-2009)

Tuesday, 09 September 2014 12:50SHAILENDER KUMAR



                     BIOCHEMISTRY ( GENERAL & OCULAR )

 Time Allotted : 3 Hours                                                                                Full Marks : 70

The figures in the margin indicate full marks.

Candidates are required to give their answers in their own words

as far as practicable.

                                                       GROUP – A

                             ( Multiple Choice Type Questions )

1. Choose the correct alternatives for any ten of the

    following :                                                                                                  10 X 1 = 10

i) Which of the following is not an essential amino acid ?

a) Phenylalanine          b) Isoleucine

c) Lysine                       d) Prothrombin.

ii) In glycolysis fluoride inhibitor, inhibits the enzyme

a) phosphotriose isomerase

b) enolase

c) lactate dehydrogenase

d) hexokinase.


iii) The number of ATP obtained in TCA cycle is

a) 30                        b) 20

c) 8                          d) 38.

  1. â
  2. á-helix is a type of

seven cycles to produce

a) 6 Acetyl CoA                  b) 4 Acetyl CoA

c) 8 Acetyl CoA                  d) 2 Acetyl CoA.

v) Deficiency of Vitamin B cause may

a) Scurvy                          b) Anaemia

c) Xeropthalmia                d) Rtarded bone growth.

vi) The origin of glucagon hormone is

a) pancreas                      b) anterior pituitary

c) adrenal cortex              d) stomach.

vii) The co-enzyme of transaminase required for

transaminatino is

a) NADP                          b) c-AMP

c) NADH                          d) PLP.

viii) The photopigment responsible for dim light vision is

a) rhodopsin                    b) iodopsin

c) melanin                        d) cyanin.

ix) Alpha-crystalline is present in

a) cornea            b) tear film

c) lens                 d) retina.


a) primary structure of protein

b) secondary structure of protein

c) tertiary structure of protein

d) quaternary structure of protein.

xi) The deoxy form of haemoglobin exist in

a) T-form            b) B-form

c) R-form            d) D-form.

xii) Albumin is synthesized in the

a) pancreas       b) stomach

c) liver               d) duodenum.

                                                           GROUP – B

                                            ( Short Answer Type Questions )

Write short notes on any three of the following.

                                                                                                                                3 X 5 = 15

2. Gamma globulins.

3. TCA cycle

4. Haemoglobin.

5. TPP as co-enzyme

6. Deamination.


                                                          GROUP – C

                                          ( Long Answer Type Questions )

Answer any three of the following.                                                                           3 X 15 = 45

7. Classify hormone on the basis of their mechanism of action.

Discuss briefly the origins & major functions of estrogen,

glucagons & glucocorticoid.                                                                                     3 + 12

8. Discuss briefly the oxidative phases of Hexose Mono

Phosphate shunt. What is the difference between

haemoglobin & myoglobin ? What is Bohr effect ?                                                  6 + 4 + 5

9. Discuss briefly about the sources of nutrients and metabolic

pathway in cornea.

10. Explain the reaction rhodopsin bleaching when light fall on

the retina. Discuss the process of β-oxidation of unsaturated

fatty acid.                                                                                                                  8 + 7

11. Deduce Michaelis-Menten equation for a single substrate

uninhibited reactor. What are the basic differences between

Michaelis-Menten equation and Birggs-Haldane theory ?

Outline the methods for determining Michaelis-Menten

constants.                                                                                                                 7 + 4 + 4


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