B.Pharm-B.Pharm 2nd Year PHARMACEUTICAL CHEMISTRY Ill(Advanced Organic Chemistry)(Kerala University of Health Sciences-2013)

            Second Year B.Pharm Degree Supplementary Examinations

                                             June 2013
                                    PHARMACEUTICAL CHEMISTRY Ill
                               (Advanced Organic Chemistry)

Time: 3 Hours                                                          Total Marks: 100

• Answer all Questions.

• Write equations wherever necessary.

 

Essay : (3x10=30)

1. Discuss the geometrical isomerism. Add a note on the modern theory of double bonds.

2. Mention poly nuclear aromatic hydrocarbons. Explain the aromatic character, electrophilic and redox reactions of naphthalene.

3. Define stereo-isomerism. Explain chirality and elements of symmetry.

 

Short notes : (14x5=70)

4. Explain the mechanism involved in Beckmann rearrangement.

5. Name the oxidising and reducing agents used in synthesis of organic reaction and mention its various applications.

6. Preparation and reactions of pyrimidine.

7. Explain the mechanism and applications of Mannich reaction.

8. Describe the stereochemistry of biphenyl compounds.

9. Walden inversion.

10. Define catalytic hydrogenation and mention its utility in synthesis.

11. Explain the mode of preparation of phenothiazine and isoquinoline.

12. Explain the nature and classification of heterocyclic compounds.

13.Outline the asymmetric synthesis with suitable example.

14.Outline the mechanism of Clemmensen's reduction.

15. Explain redox reaction of naphthacene.

16. Define azepines and explain its method of preparation.

17. Mechanism of Hoffman rearrangement.

Earning:  ₹ 8.00/-