B.Pharm-B.Pharm 2nd Year APPLIED BIOCHEMISTRY and MOLECULAR BIOLOGY(Kerala University of Health Sciences-2013)

      Second Year B.Pharm Degree Supplementary Examinations - June 2013 
                     APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY 

Time: 3 Hours                                                                       Total Marks: 100 

• Answer all Questions. 

• Draw diagrams wherever necessary. 

Essay (3x10=30) 

1. What are eicosanoids. Discuss the chemistry and biosynthesis of eicosanoids. 
(2+4+4=10) 

2. What are enzymes. Explain the influence of substrate concentration on enzyme activity with Michaelis plot. (2+8=10)

3. Explain the pathways involved in glycogen metabolism (glycogenolysis and glycogenesis) (5+5=10) 

Short notes (14x5=70)

4. Define carbohydrates and how are they classified. 

5. Genetic code. 

6. Briefly discuss the denovo synthesis of purine nucleotides. 

7. DNA replication. 

8. Explain the metabolism of sulphur containing amino acids. 

9. Catabolism of tryptophan and its metabolic disorders. 

10. Explain the metabolism of cholesterol. 

11. Explain the structure and functions of chromosomes. 

12. How will you determine the change in free energy from equilibrium 

13. Explain the enzyme inhibitors with example. 

14. Gluconeogenesis and its significance. 

15. Explain transcription and translation 

16. What are phospholipids and its significance. 

17. Synthesis and significance of creatine. 

 

Earning:  ₹ 7.50/-