North Maharashtra University 2008 B.Sc Biotechnology S.Y- : BT 212- MOLECULAR BIOLOGY - Question Paper

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NORTH MAHARASHTRA UNIVERSITY, JALGAON

ques. Paper :-

CLASS- S.Y.B.Sc SEMESTER-I

PAPER: BT 212- MOLECULAR BIOLOGY

CELL BIOLOGY AND BASIC METABOLISM
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Q.1 ques. for two Marks (Objective).
1) The most conserved histones are………….
a) H1 & H2A b) H2A & H2B
c) H3 & H4 c) H1 & H4.
2) The E-coli circular DNA packaged into region of cell called…….
a) Nucleus b) Cytoplasm
c) Nucleolus d) Nucleoid.
3) The prokaryotic translation begin with……… initiation codon.
a) UAG b) AUC
C) AUG d) GUA.
4) The triplet of bases current on specific t-RNA molecules are………
a) anticodon b) Synonyms
c) codon d) Stop codon.
5) The chromatin is more dispersed during………….
a) Meiosis b) Interphase
c) Mitosis d) M-Phase
6) The nuclear DNA-protein complex is called………..
a) Chromosome b) Nucleoprotein
c) Chromatin d) None.
7) ……… are non coding sequence current in m-RNA molecules.
a) Introns b) Stop sequence
c) Exon d) None.
8) …………is due to less stringent pairing of 3rd base of codon with
anticodon.
a) Degeneracy b) Mutation
c) Wobbling d) Universality.

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9) The sequence of m-RNA transcribed & translated is known as……….
a) Non coding sequence b) Exon
c) Mid sequence d) Intron
10) ……….. is the distinct sequence of a DNA molecule forming part of
chromosome.
a) Gene b) Chromatin.
c) Nucleotide d) Genome.
11) Nucleosome core particle contains a double stranded DNA fragment of
………base pairs.
a) 148 b) 144
c) 156 d) 146.
Q.2 ques. for two Marks (Short answer).
1) describe Nucleosomes.
2) discuss Histones protein?
3) Comment on concept of Gene.
4) describe Intron.
5) Comment on Exon as an important part of m-RNA.
6) discuss role of Non Histone proteins.
7) describe – a) Chromatin b) Chromosome
8) describe Genetic code & Codon.
9) discuss degeneracy of genetic code.
Q.3 ques. for three Marks
1) discuss how Histine protein is important in DNA packaging?
2) What is Intron? discuss its kinds.
3) Comment on propeties of genetic code.
4) explain nucleosomes as fundamentle unit of DNA organization.
5) Comment on organization of Chromatin.
Q.4Question for four Marks
1) Distinguish ranging from Histone & Non histone proteins.
2) discuss Degeneracy & wobbling of genetic code.

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3) discuss detail structure of Nucleosome.
4) explain the importance of chromatin organization.
5) What is gene? discuss concept of gene briefly.
6) Compare: Chromatin organization in Prokaryote & Eukaryote.
Q.5 ques. for six Marks.
1) define nature & properties of genetic code.
2) What is splicing? discuss Intron with self splicing activity.
3) What is Chromatin? discuss its organizatin.
4) discuss the process of nucleosome formation.

Earning:   Approval pending.