Jawaharlal Nehru Technological University Kakinada 2010 B.Pharm Pharmaceutical Organic Chemistry-I - Question Paper

B. Pharm [JNTU (K)]
First Year Regular Examination, May 2010
Pharmaceutical Organic Chemistry-I

Time: three Hours Max. Marks: 80

Note:
1) Answer any 5 ques. from the subsequent.
2) All ques. carry equal marks.

1) What are Carboxylic Acids? Write about Methods of Preparation and Important Reactions. discuss the Acidity of Carboxylic Acids?

2) a) Give General Methods of Preparation and Important Reactions of Alcohols.
b) How do you distinguish ranging from 1°, 2°, and 3° Alcohols?

3) Write a note on:
a) Stability of Free Radicals.
b) Electrophilic Aromatic Substitution Reactions.
c) Nucleophilic Addition Reaction.
d) Stability of Phenoxide Ion.

4) Define Saytzeff's Rule. discuss Mechanism and Substitution Reactions of SN1 and SN2 in detail.

5) a) Write about brief account of Malonic and Acetoacetic Esters.
b) Explain the Structure of Naphthalene and Anthracene.

6) a) What are Amines? Write the General Methods of Preparation of Amines.
b) Explain the Hinsberg Method for the Separation of Amines.

7) Write the Reaction with Mechanism involved in following:
a) Bayer's Oxidation
b) Reformatsky Reaction
c) Perkins Reaction
d) Aldol Condensation

8) a) Give the General Methods of Preparation and Important Reactions of Cyclo Alkanes.
b) Explain Electrophilic Addition Reactions of Alkenes.
c) Explain Acidity of Phenols.
d) Explain Theory of Resonance.

Earning:   Approval pending.