All India Institute of Medical Sciences 2003 - Question Paper

5) OPTIC GLIOMA
6) Sphenoid dysplasia or thinning of cortex of long bones.
7) Immediate Relative with Neurofibromatosis kind 1
Since, optic nerve glioma is 1 of the diagnostic criterai for NF one it is the commonest. Other tumours associated with NF1 are Astrocytic tumours, neurofibrosarcomas, pheochromocytoma. Compressive myleopathy, compressive peripheral neuropathy and scoliosis also occur.
NF kind two is also Autosomal dominant, the defect being loacted on chromosome 22. It is characterized by bilateral acoustic neuromas. (remember kind two -22 chromosome) / (type 1-17 chromosome)

15. A patient undergoing surgery suddenly develops hypotension. The monitor indicates that the end tidal carbon dioxide has reduced abruptly by 15mmHg. What is the probable diagnosis?
1. Hypothermia.
2. Pulmonary embolism
3. Massive fluid deficit
4. Myocardial depression due to anesthetic agents.
Ans 2

16. The commonest reason of death in a patient with primary amyloidosis is
1. Renal failure
2. Cardiac involvement
3. Bleeding diathesis
4. Respiratory failure
Ans 1

17. A middle aged old man, with chronic renal failure is diagnosed to have sputum positive pulmonary tuberculosis. His creatinine clearance is 25ml/min. All of the subsequent drugs need modification in doses other than.
1. Isoniazid
2. Streptomycin
3. Rifampicin
4. Ethambutol.
Ans three Rifampin has hepatic metabolism, Isoniazid has hepatic metabolism but dose ¯ needed in mild to moderate renal failure. Streptomycin & ethambutol have RENAL metabolism.


18. An HIV- positive patient is on anti retroviral therapy with zidovudine, lamivudine and indinavir. He is proven to be suffering from genitor- urinary tuberculosis. Which 1 of the subsequent drugs not is provided to this patient?
1. Isoniazid
2. Rifampicin
3. Pyrazinamide
4. Ethambutol
Ans two As Rifampin is an enzyme inducer.

19. A high amylase level in pleural fluid suggests a diagnosis of :
1. Tuberculosis
2. Malignancy
3. Rheumatoid arthritis
4. Pulmonary infarction
Ans 2. High amylase in pleural fluid may also be seen in pancreatic pleural effusion and esophageal rupture q

20. Which of the subsequent conditions is associated with Coomb's positive hemolytic anaemia:

Earning:   Approval pending.