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All India Institute of Medical Sciences 2003 Post Graduate Diploma all india medical pre pg entrance - Question Paper

Friday, 01 February 2013 08:15Web
3.Injury to deltoid ligament.
4.Shortening of planter aponeurosis.

Ans.?1
18. The main enzyme responsible for activation of xenobiotics is:
1.Cytochrome P-450
2.Glutathione S-transferase.
3.NADPH cytochrome P-450-reductase.
4.Glucuronyl transferase.
Ans. three [ Harper ed 23rd page 705 Chapter 61-Xenobiotics Mentions that NADPH cytochrome P-450-reductase is involved NOT NADH]
19. The primary defect which leads to sickle cell anemia is:
1.An abnormality in porphyrin part of hemoglobin.
2.Replacement of glutamate by valine in B-chain of HbA.
3.A nonsense mutation in the B-chain of HbA.
4.Substitution of valine by glutamate in the a-chain of Hba.
Ans. 2
20. A 40 years old lady delivered a full term baby. On exam of the baby, the neonatologist noted certain urogenital abnormality. He took the subsequent the picture. The most likely diagnosis is:
1.Urogenital sinus.
2.Hypertrophied clitoris.
3.Miocropenis.
4.Vulval hematoma.

Ans. two [ref: picture in OP Ghai ]



21. reduced Glycolytic activity impairs oxygen transport by hemoglobin due to:
1.Reduced energy production.
2.Decreased production of 2,3-bisphosphoglycerate.
3.Reduced synthesis of hemoglobin.
4.Low levels of oxygen.
Ans. 2
22. The primary role of chaperones is to help in:
1.Protein synthesis.
2.Protein degradation.
3.Protein denaturation.
4. Protein folding.
Ans. 4
23. The conversion of an optically pure isomer (enantiomer) into a mixture of equal amounts of both dextro and levo forms is called as:
1.Polymerization.
2.Stereoisomerization.
3.Racemization.
4.Fractionation.
Ans. 3
24. The protein rich inbasic amino acids, which functions in the packaging of DNA in chromosomes, is:
1.Histone.
2.Collagen.
3.Hyaluronic acid binding protein.
4.
Ans.1
25. A 56 year old man presents in the casualty with severe chest pain and difficulty in breathing. His ECG was taken immediately.\
The above ECG suggest the subsequent diagnosis:
1.Ventricular fibrillation.
2.Acute pulmonary embolism.
3.Second degree heart block.
4.Atrial fibrillation.

Ans. ? [ Here ECG appears insignificant, as history is suggestive of PE] [other view - Varying R - R interval which can only be in 3/4 choice]
26. An enzyme involved in the catabolism of fructose to pyruvate in the liver is:
1.Glyceraldehyde-3-phosphate Dehydrogenase.



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