All India Institute of Medical Sciences 2009 M.D Pathology AIPG - Question Paper

PATHOLOGY

Q1. Finnish kind of nephritic syndrome is associated with:
a- Nephrin
b- Podocin
c- Alpha actinin
d- CD2 activated protein
Ans: a.

Q2. A 7-year old girl presents with bleeding in joints. She has prolonged aPTT, normal PT an platelet counts. What could be the deficiency?
a- IX
b- VIII
c- VII
d- Von Willebrand
Ans: d.

Q3. Which of the subsequent is not actual about Neuroblastoma?
a- Most common extracranial solid tumor in childhood
b- >50% current with metastasis at time of diagnosis
c- Lung metastases are common
d- Involve aorta and its branches early
Ans: d.

Q4. Function of CD4, is all except:
a- Memory
b- Immunoglobin production
c- Activation of macrophages
d- Cytotoxicity
Ans: b.

Q5. What is specific for GIST?
a- CD 117
b- CD34
c- CD23
d- S-100
Ans: a.

Q6. actual for hemochromatosis:
a- Complete penetrance
b- Autosomal recessive
c- Phlebotomy leads to cure
d- More common in females
Ans: b.

Q7. When 1 gene is inherited from 1 parent only, it is known as:
a- Genomic imprinting
b- Mosaicism
c- Alleles
d- Chimerism
Ans: a.

Q8. Pauci-immune crescentic glomerulonephritis is associated with:
a- Microscopic polyangitis
b- SLE
c- H S Purpura
Ans: a.

Q9. What is affected in HbS (Hemoglobin S)?
a- Stability
b- Function
c- Affinity
d- Solubility
Ans: d.

Q10. A 56-year-old male presents with sudden substernal pain, impending doom, died days after. On autopsy, there was a large transmural anterior wall infarction. It would be associated with:
a- Presence of collagen and fibroblasts
b- Presence of neutrophils
c- Granulomatous inflammation
d- Granulation tissue
Ans: d.

Q11. Characteristic of acute inflammation:
a- Vasodilation and increased vascular permeability
b- Vasoconstruction
c- Platelet aggregation
d- Infiltration by neutrophil
Ans: a.

Q12. Coagulative necrosis is obtained in which infection?
a- TB
b- Sarcoidosis
c- Gangrene
d- Fungal infection
Ans: a.

Q13. Psammoma bodies are seen in all except:
a- Follicular carcinoma thyroid
b- Papillary carcinoma thyroid
c- Serous cystadenoma
d- Meningioma
Ans: a.

Q14. Stain of mineralization of newly formed osteoid:
a- von Kossa stain
b- Alizarin red
c- tagged tetracycline
d- Fluorescence
Ans: c.

Q15. Colon Ca is associated with all except:
a- Rb
b- Mismatch repair genes
c- APC
d- Beta detenin
Ans: a.

Q16. Hallmark features of benign HTN is:
a- Hyaline arteriosclerosis
b- Cystic medial necrosis
c- Fibrinoid necrosis
d- Hyperplastic art
Ans: a.

Q17. Organelle which plays a pivotal role in apoptosis:
a- Cytoplasm
b- Golgi complex
c- Mitochondria
d- Nucleus
Ans: c.

Q18. Most bactericidal agent is:
a- Cationic basic protein
b- Lactoferrin
c- Lysozyme
d- Reactive O2 species
Ans: d.

Q19. Hypersensitive pneumonitis is classically a:
a- Allergic reaction
b- kind II hypersensitivity
c- Immune complex mediated hypersensitivity
d- Cell mediated hypersensitivity
Ans: c.

Q20. Karyotyping is done for:
a- Chromosomal disorders
b- AR disorders
c- AD disorders
d- Link disorders
Ans: a.

Q21. Aging is due to:
a- Accumulated mutations in somatic cells
b- Accumulation of free radicals
c- reduced cross linking of collagen
d- reduced antioxidant
Ans: a.

Earning:   Approval pending.