Gujarat Technological University 2010 M.Pharm el Drug Delivery System Part-I - Question Paper
Seat No. Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Pharmacy Sem-II Examination July 2010
Subject code: 920102 Subject Name: Novel Drug Delivery System Part-I Date: 05 /07 /2010 Time: 11.00 am - 02.00 pm
Instructions: Total Marks: 80
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
What is gastro-retentive drug delivery? How it can be achieved? Write a note on 06 floating drug delivery system.
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Discuss the rationale underlying the design of gastro retentive dosage forms. 05 What type of GRDDS do you suggest for delivery of Levodopa and diazepam with suitable scientific explanation? Discuss in detail such dosage forms.
Explain the structure of buccal mucosa. Give a brief account of mucoadhesive 05 polymers for buccal delivery.
Write the rational behind colon specific drug delivery system. Discuss in brief 06 various approaches used for colonic drug delivery system.
Enlist the factors to be considered in the design of colon-specific drug delivery 05 system. Discuss about evaluation of colon specific drug delivery system.
Discuss the merits and demerits of mucoadhesive buccal drug delivery. How one 05 can evaluate mucoadhesive buccal formulation?
Discuss about advances in particle coating technology. 06
Enlist recent innovations in advances in capsules. Describe any one in detail. 05
Suggest the excipients suitable for osmotic drug delivery system. Which APIs 05 can be formulated by this approach? Why?
Which factors are to be considered in selection of glass containers? Describe the 06 test for evaluation of suitability of glass as a container per USP standards.
What do you mean by AAO recommendations for color coding? Write a note on 05 films, foils and laminates.
Define pharmaceutical package. Enlist the criteria for selection of package type 05 and packaging material. Classify the packaging materials.
Write a note on child resistant and temper proof packaging. 06
Discuss in brief intravaginal drug delivery system. Discuss the advantages and 05 disadvantages of vaginal drug delivery system and enlist the factors affecting vaginal absorption.
Write a note on erodible ocusert. 05
Give commonly used techniques for development of parenteral controlled release 06 formulations. Discuss in detail about dissolution controlled and adsorption type depot formulation.
What is liposome? Enlist the material used for preparation of liposome. Write 05 about any one method of preparation.
Write a note on application of nanoparticles. 05
Discuss the strategies developed for oral administration of drugs through hydrogel 06 designed for controlled release.
Write a note on hydrophilic contact lenses as an ophthalmic drug delivery system. 05 Enlist various approaches employed for taste masking. Explain in detail about 05 chemical approach.
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