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Gujarat Technological University 2012-2nd Sem M.Pharm - – –, Advances in Pharmaceutical Science - Question Paper

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Univesity Name: Gujrat Technological University
Paper name: Advances in Pharmaceutical Science
Academic Year: 2012
Courses: M.Pharm 2nd semester exam


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Seat No.:__Enrolment No._

GUJARAT TECHNOLOGICAL UNIVERSITY

M.PHARM- SEM-II-EXAMINATION - JULY 2012 Subject code: 2920205    Date: 09/07/2012

Subject Name: Advances in Pharmaceutical Science

Time: 10:30 am - 01:30 pm    Total Marks: 80

Instructions:

1.    Attempt any five questions.

2.    Make suitable assumptions wherever necessary.

3.    Figures to the right indicate full marks.

Q.1

(a)

Enlist various brain disorders and give the detail of plants and phytoconstituents for brain tonic activity.

06

(b)

Write short note on diuretic plants.

05

(c)

Give the detail of phytoconstituents as hepatoprotective.

05

Q2

(a)

Explain the mechanism of action of following drugs as an

06

anticancer.

1.    Vincristine

3.    Etoposide

(b)

Define and classify nutraceuticals with suitable examples.

05

(c)

Write brief note on polyunsaturated fatty acid as nutraceuticals.

05

Q.3

(a)

Enlist the various plants for antidiabetic activity and give its biological source and chemical constituents.

06

(b)

Explain the different models for screening of antioxidant activity.

05

(c)

Classify the cardiac glycoside with suitable examples and explain the mechanism of action of cardiac glycoside.

05

Q.4

(a)

Explain the differentiating chemical tests between following phytoconstituent.

06

1.    Cardenolide and bufadienolide

2.    Steroidal saponin and triterpenoid saponin

3.    O- glycoside and C- glycoside

(b)

Write short note on Guggul

05

(c)

Explain the importance of thin layer chromatography in plant drug analysis.

05

Q.5

(a)

Write brief note on Curcumin and Digoxin

06

(b)

Define pesticide and explain the methods for pest control.

05

(c)

Give the detail of secondary metabolites of plant for pesticide.

05

Q. 6

(a)

Explain immunomodulating activity of Galo and Ashwagandha.

06

(b)

Discuss various phytoconstituents used for HIV infection.

05

(c)

Explain the importance of Soya product for the health benefit.

05

Q.7

(a)

Explain phytochemical screening of Alkaloid, Flavonoid and Tannin

06

(b)

Explain the mechanism of action of Artemisin for anti-malarial activity.

05

(c)

Enlist the different models for evaluation of antiulcer and antiinflammatory activity.

05







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