Gujarat Technological University 2009-2nd Sem B.Pharm acy Remedial (Pharmachemistry-II) - Question Paper
Seat No. Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem-II Remedial Examination September 2009
Subject code: 220003 Subject Name: Pharm Chemistry II
Date: 08/09/2009 Time: 10:30am-1:30pm
Total Marks: 80
Instructions:
1. Write seat no. and enrolment no. at given location on question paper.
2. Attempt any five questions.
3. Make suitable assumptions wherever necessary.
4. Figures to the right indicate full marks.
Q.1 Answer the followings
(a) What is surface tension? Derive equation to determine Surface 06 tension by capillary rise method.
(b) Define Refractive Index. How is it determined? Give its 06 applications.
(c) Define the terms: 04
(i) Specific Optical Rotation (ii) Partition-coefficient
(iii) Reverse Osmosis (iv)Activation Energy
Q.2 Answer the followings
(a) State and explain Raoults law for dilute solution. Discuss deviations 06 of real solution from the Raoults law.
(b) The osmotic pressure of a solution containing 1.0 gram of purified 06 hemoglobin in 50 ml of water is 5.40 mm of Hg at 25 degree centigrade. What is the molecular weight of hemoglobin?
R= 0.0821 L. atm. / mole/ K.
(c) An aqueous solution freezes at -3.07 C. At what temperature will 04 this solution boil? ( water Kf =1.86, kb=0.51)
Q.3 Answer the followings
(a) What is adsorption? Derive the equation for Langmuirs adsorption 06 isotherm.
(b) Enumerate the pharmaceutical application of Adsorption in 06 pharmacy. Discuss any two.
(c) Differentiate physical and chemical adsorption. 04
Q.4 Answer the followings
(a) Explain order of reaction and derive equation of first order kinetic. 06 Give characteristic of first order kinetics.
(b) Syrup contained 500 mgs of drug / ml when prepared and after 30 06 days was found to contain 400 mgs/ ml. The drug was decomposed
by first order kinetic. What is half life of drug?
(c) Out line importance of Rate process in pharmacy. 04
Q.5 Answer the followings
(a) Define specific conductivity and equivalent conductivity. Write note 06 on Debye-Huckel theory.
Compare properties of Radioactive Rays.
What are the methods of Measurements of Radioactivity? Discuss any one method.
(b)
(c)
(a)
(b)
(c)
(a)
Answer the followings
Draw Jablonski diagram .State Beers Law of photometry. Calculate absorbance corresponding to 0, 10 and 100 % transmission.
06
06
04
Explain the term phase, component, and degree of freedom with illustration State and explain phase rule.
Discuss phase diagram of system containing phenol-water.
Answer the followings Explain the terms
Q.7
06
(i) Heat of Formation
(ii) Heat of solution
(iii) Heat of fusion
(iv) Heat of N eutralization
Explain term; Free energy, Lattice energy and Entropy. Discuss application of the thermodynamics in solubility of solid in liquid. The standard Heat of formation of C2H5OH q , CO2(g) and H2O (l) are -277.0 , -393.5 & -285.5 KJ /mol respectively. Calculate heat of combustion of ethanol.
(b)
(c)
06
04
2CO2(g) + 3H2O
2(g)
(l)
C2H5OH (l) + 3O
2
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