Gujarat Technological University 2009-1st Sem B.Pharm acy Remedial (Pharmachemistry-I) - Question Paper
Seat No. Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem-I Remedial examination March 2009
Subject code: 210003 Subject Name: Pharm Chemistry-I
Date: 17 / 03 /2009 Time: 10:30am-1:30pm
Instructions: Total Marks: 80
1. Attempt any five questions.
Make suitable assumptions wherever necessary.
2.
3.
Q.1
Figures to the right indicate full marks.
(a) Define the term impurity. Discuss importance of limit test in pharmacy. Explain the principle involved in the limit test of arsenic giving the reactions and role of reagents used.
(b) Discuss the sources of impurities in pharmaceuticals.
Q.2 (a) Explain Bronsted-Lowery acid-base theory. What is a conjugate ac id and base.
(b) What is meant by physiological buffers ? Describe the mechanism of maintaining pH of blood.
(c) Discuss biological importance of calcium ions and their deficiency symptoms.
Q.3 (a) Define the following terms:
(i) Emetic (ii) Sclerosing agent (iii) Suspending agent.
(iv) Preservative. (v) Adsorbent
(b) Give the name and structure of any one compound used as
(i) Astringent. (ii) Purgative. (iii) Emetic.
(iv) Hematinic (v) Expectorant
(c) Give the chemical name, structural formula and use of the following.
(i) Backing soda. (ii) Chlorinated lime. (iii) Epsom salt.
(iv) Green vitriol. (v) Lunar caustic. (vi) Alum
Q.4 (a) Classify inorganic compounds acting as gastrointestinal agents giving examples.
(b) What are antacids? Outline the ideal requirements of an antacid.
(c) Give methods of preparation and use of aluminum hydroxide gel and milk of magnesia.
Q.5 (a) What are topical agents ? Classify topical agents giving examples.
(b) Explain the mechanism of action of inorganic antimicrobial agents.
(c) Describe the preparation and uses of potassium permanganate and Calamine lotion.
Q. 6 (a) Enumerate official compounds of Iron. Give preparation and uses of ferrous gluconate and ferric ammonium citrate.
(b) What are intra and extra cellular electrolytes? What is meant by oral rehydration therapy?
(c) What are antidotes? What is the mechanism of action of antidote in poisoning ?
Q.7 Write short notes on: (Any FOUR )
(a) Anticarries agents.
(b) Antioxidants.
(c) Limit test of Iron.
(d) Inhalants.
(e) Respiratory stimulants
(f) Povidone iodine.
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