Gujarat Technological University 2010 B.Pharm Pharmaceutics-II - exam paper

B. Pharm
Second Semester Examination, June 2010
Subject Code - 220002
Pharmaceutics-II

Time: three Hrs. Total Marks: 80
Instructions:
1) Attempt any 5 ques..
2) Make suitable assumptions wherever necessary.
3) Figures to the right indicate full marks.

Ques one a) define the factors affecting the process of size reduction. (07)
Ques one b) explain the different theory to estimate the energy needed for size reduction process. (06)
Ques one c) What is Angle of Repose? provide its significance. (03)

Ques two a) define standards of sieve. How powders are are classified according to size as per Indian Pharmacopeias? (06)
Ques two b) define construction, working and uses of fluid energy mill. (05)
Ques two c) define construction and working of cyclone separator. (05)

Ques three a) discuss terms with examples, positive, negative, and neutral mixture. (06)
Ques three b) explain the factors which controls the solid-solid mixing. (05)
Ques three c) provide mechanisms of solid-solid and liquid-liquid mixing. (05)

Ques four a) define construction, working, and uses of triple roller mill. (06)
Ques four b) discuss crystal forms and crystal habits with suitable example. (05)
Ques four c) explain the factors that affect the formation and growth of crystal. (05)

Ques five b) define the miers super saturation theory of crystallization. elaborate the limitations of the miers theory? (06)
Ques five b) With tagged diagram of Swenson-Walker crystallizer, discuss its working. elaborate its advantages over other crystallizer? (05)
Ques five c) What is polymorphism? provide its examples. (05)

Ques six a) Enumerate solvents employed for vegetable drugs. Compare them. (06)
Ques six b) With the help of a tagged diagram, define the soxhlet extractor for continuous hot extraction. (05)
Ques six c) explain the role of lubricants in tablet formulation. (05)

Ques seven a) define various devices available for measurement of pressure. (06)
Ques seven b) elaborate safety precautions to be observe in pharmacy laboratory? (05)
Ques seven c) explain the factors affecting strength of compressed tablets. (05)

Earning:   Approval pending.