Gujarat Technological University 2009 B.Pharm Pharmaceutics-II - exam paper

B. Pharm (GTU)
Second Semester Examination, June-2009
Pharmaceutics-II
Time: three Hours Total Marks: 80
Instructions:
1) Attempt any 5 ques..
2) Make suitable assumptions wherever necessary.
3) Figures to the right indicate full marks.

Ques 1) a) describe Polymorphism. explain the significance of Polymorphism in Pharmacy with example.
(06)
b) Discuss the 2 component systems containing solid and liquid Phases. (06)
c) Write a note on liquid Crystals. (06)
Ques 2) a) What is Buffer capacity? How it is calculated? (07)
b) Write a note on Pharmaceutical Buffer. (05)
c) Calculate the pH of 0.02 M Ba(OH)2. (04)
Ques 3) a) Write in detailed note on Non-Newtonian systems. (05)
b) Classify different viscometers. define 2 viscometer with diagram to obtain out viscosity of Non-Newtonian fluids. (06)
c) What a note on: Plastic and Pseudoplastic flow. (05)
Ques 4) a) Differentiate different kinds of colloidal dispersion system and provide the application of colloids in pharmacy. (07)
b) Define Suspension. Write a note on factors affecting stability of Suspension. (05)
c) Discuss the instability of emulsions. (04)
Ques 5) a) explain the method of determining the particle quantity in detail. (06)
b) Discuss the porosity and Kelvin formula with their significance in pharmacy. (06)
c) A sample of calcium carbonate having density 2.8 g/cm3, allow to settle under acceleration of gravity (gc = 980 cm/sec) the rate of setting (v) is 14.6 × 10-3 cm/sec, the density (?) of water is 1.00g/cm3 and viscosity (?) is 0.01 poise. compute the Stoke's Diameter. (04)
Ques 6) a) discuss the Surface and Interfacial tension. (05)
b) What is spreading Coefficient? Derive its formula. (06)
c) Describe the method of computation of HLB by various techniques. (05)
Ques 7) a) Write a note on solubility of gases in liquid. (05)
b) Write a note on legal regulations of distribution. (06)
c) Write a note on physical stability of emulsion.

Earning:   Approval pending.