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Gujarat Technological University 2011 B.Pharm Pathophysiology - Question Paper

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Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem-III Regular / Remedial exam Dec. 2010
Subject code: 230005 Subject Name: Pathophysiology
Date: 18 / 12/ 2010 Time: 10.30 am – 01.30 pm
Instructions: Total Marks: 80
1. Attempt any 5 ques..
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) discuss the terms:
1. hypertrophy
2. Atrophy
3. Hyperplasia
4. Necrosis
06
(b) Write in detail about mechanism of cell injury. 05
(c) Write a note on Amyloidosis. 05
Q.2 (a) describe apoptosis. Write in detail about mechanism of apoptosis. 06
(b) define in detail about growth factors involved in tissue repair. 05
(c) Write a note on obesity. 05
Q.3 (a) describe acute inflammation. Write in detail about cell events occur in acute
inflammation.
06
(b) Write in detail about mechanism of autoimmunity. 05
(c) Write a note on protein energy malnutrition. 05
Q.4 (a) discuss the terms:
1. Natural killer cell
2. Dendritic cell
3. T lymphocyrtes
4. MHC molecule
06
(b) Write in detail about mechanism of intracellular accumulation. 05
(c) Write a note on therapeutic drugs induced adverse reactions. 05
Q.5 (a) describe immunity. Write in detail about adaptive immunity. 06
(b) Write in detail about mechanism of tissue repair. 05
(c) Write a note on metals as environmental pollutants. 05
Q.6 (a) Write in detail about mechanism of antibody mediated disease. 06
(b) Write in detail about stimuli for acute inflammation. 05
(c) Write a note on components of extracellular matrix. 05
Q.7 (a) Write in detail about effector mechanism of graft rejection. 06
(b) Write in detail about cell derived mediators of inflammation. 05
(c) Write a note on systemic lupus erythromatous. 05
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