Gujarat Technological University 2010 B.Pharm Pharm Chemistry II - Question Paper

Q.1 ans the followings
(a) What is surface tension? Derive formula to determine Surface
tension by capillary rise method.
06
(b) describe Refractive Index. How is it determined? provide its
applications.
06
(c) describe the terms:
(i) Specific Optical Rotation (ii) Partition-coefficient
(iii) Reverse Osmosis (iv)Activation Energy
04
Q.2 ans the followings
(a) State and discuss Raoult's legal regulations for dilute solution. explain deviations
of real solution from the Raoult's legal regulations.
06
(b) The osmotic pressure of a solution containing 1.0 gram of purified
hemoglobin in 50 ml of water is 5.40 mm of Hg at 25 degree
centigrade. What is the molecular weight of hemoglobin?
R= 0.0821 L. atm. / mole/ K.
06
(c) An aqueous solution freezes at –3.07 °C. At what temperature will
this solution boil? ( water Kf =1.86, kb=0.51)
04
Q.3 ans the followings
(a) What is adsorption? Derive the formula for Langmuir's adsorption
isotherm.
06
(b) Enumerate the pharmaceutical application of Adsorption in
pharmacy. explain any two.
06
(c) Differentiate physical and chemical adsorption. 04
Q.4 ans the followings
(a) discuss order of reaction and derive formula of 1st order kinetic.
provide characteristic of 1st order kinetics.
06
(b) Syrup contained 500 mgs of drug / ml when prepared and after 30
days was obtained to contain 400 mgs/ ml. The drug was decomposed
by 1st order kinetic. What is half life of drug?
06
(c) Out line importance of Rate process in pharmacy. 04
Q.5 ans the followings
(a) describe specific conductivity and equivalent conductivity. Write note
on Debye-Huckel theory.
06

Earning:   Approval pending.