Gujarat Technological University 2010 B.Pharm Pharmaceutics-II - Question Paper

Q.1 (a) Comment: Fluid energy mill is suitable for grinding thermolabile
materials.
02
(b) define colloid mill with working diagram. 04
(c) define ball mill with working principle. 05
(d) define theories for energy requirement in size reduction. 05
Q.2 (a) Comment: When vegetable drugs are ground and sifted, none must
be rejected.
02
(b) discuss angle of repose, Carr's Index and Hausner ratio with
significance.
04
(c) define pharmacopoeial standards for sieves. 05
(d) discuss elutriation. define multistage elutriation process. 05
Q.3 (a) Comment: Turbine mixers are suitable for emulsification. 02
(b) define the factors affecting powder mixing. 04
(c) Enlist mixers for semisolids. define planetary mixer. 05
(d) Classify liquid mixers. define propeller mixers. 05
Q.4 (a) discuss Co-crystals with examples 02
(b) discuss nucleation. define factors affecting crystal growth. 04
(c) define Mier's theory for supersaturation with limitations. 05
(d) define Swenson- Walker crystallizer with diagram. 05
Q.5 (a) discuss Extraction and Manstrum. 02
(b) explain methods of solvent recovery in extraction process. 04
(c) define Soxhlet apparatus for extraction. 05
(d) compute the % crystal yield of glauber salt (Na2SO4-10 H2O) if a
pure32% solution is cooled to 20 oC without any evaporative loss.
(Solubility of glauber salt is 19.4 gm/ 100 gm water).
05
Q. six (a) Differentiate: Compaction and Consolidation. 02
(b) explain Heckel and Kawakita's formula w.r.t. compression. 04
(c) define various phases of compression for tableting. 05
(d) define Direct Compression technology for tablet manufacturing. 05
Q.7 (a) discuss automated process control. explain key elements for the
same.
04
(b) define automation for temperature control. 04
(c) Write brief note on fire extinguishers. 04
(d) define methods for waste water treatment in pharmaceutical
industry
04

Earning:   Approval pending.