Gujarat Technological University 2010 B.Pharm Pharmaceutical Chemistry-III - Question Paper

Q.1 (a) Write a note on: halogenations of Alkanes 06
(b) describe hybridization? discuss Sp2 hybridization with example. 05
(c) discuss subsequent Terms
1. Heterolysis
2. Homolysis
3. Dipole-Dipole interaction
4. Antibonding orbital
5. Steric effect
05
Q.2 (a) Distinguish the subsequent
1. 1-Hexene and n-Hexane
2. Propene and propane
3. Acetylene and Ethylene
06
(b) define preparation and synthetic utility of Grignard reagent 05
(c) Write a note on Williamson's synthesis of ether. 05
Q.3 (a) explain mechanism of SN1 and SN2 reactions of alkyl halides 06
(b) Explian the subsequent
1. Carbenes as reaction intermediates
2. Carbocations with mechanism
05
Q.4 (a) How will you distinguish ranging from primary, secondary and teritary
alchol.
06
(b) Write a note on the subsequent
1. Sigmatropic reactions
2. Neighbouring group effects
05
(c) discuss dehydration of alcohol with example for supporting its
orientation.
05
Q.5 (a) provide general methods for the preparation of Alkyne and Alkene 06
(b) How Hyperconjugation and resonance differ from every other?
explain with example.
05
(c) provide structural formula for the subsequent
1. 2-methoxypentane
2. N-butyl methyl ether
3. 2-methyl-2-butene
4. Vinyl bromide
5. 1-methoxy-2-propanol
05
Q. six (a) describe the subsequent
1. Markonikov's rule
2. Ozonolysis
3. Peroxide effect
06
(b) provide general methods for the preparation of Alkyl halide 05

Q.7 (a) Method of preparation of cycloalkanes. 06
(b) Write a note on the subsequent
1. Aldol condensation
2. Clasien condensation
05
(c) An organic substance on analysis was obtained to contain 10.06 per
cent carbon, 0.84 percent hydrogen and 89.10 per cent chlorine.
compute its empirical formula
05

Earning:   Approval pending.