Gujarat Technological University 2010 B.Pharm Pharmaceutical chemistry - I - Question Paper

Q.1 (a) What do you mean by impurities? discuss the importance of limit
test in Pharmaceutical Preparation. discuss the principle of limit test
for Iron.
06
(b) describe subsequent terms with illustration
1. Respiratory stimulant 2. Sedative 3. Suspending agent
4. Cathartics 5. Pharmaceutical aids
05
(c) provide the synonyms and uses of subsequent
1. Common salt 2. Chlorinated lime 3. Baking soda
4. Rochelle salt 5. Slaked lime
05
Q.2 (a) explain the factors affecting selection of Pharmaceutical buffers and
name any 2 physiological buffers and 2 analytical buffers.
06
(b) Write Assay Principle and chemical reaction of subsequent
1. Zinc oxide 2. Boric acid 3. Ammonium chloride
06
(c) What is meant by
1. Official Compound 2. Pharmacopoeia 3. Buffer solution
4. Hard water
04
Q.3 (a) Classify antimicrobial agents with example and explain its
mechanism of action
06
(b) Write the storage condition
1. Oxygen 2. Phosphoric acid 3. Silver Nitrate 4. Iodine
05
(c) Write a note on
1. Dental Products 2. Antidotes
05
Q.4 (a) Comment on subsequent
1. Manganese dioxide is used in preparation of iodine from kelp.
2. Glycerin is added in assay of Boric acid.
3. Aqueous Ammonia is added in limit test of lead
06
(b) Classify subsequent
1. Saline cathartics 2. Antioxidants
05
(c) discuss the subsequent terms
1. Astringent 2. Emetics three Hygroscopic
4. Deliquescence 5. Efflorescence
05
Q.5 (a) Distinguish ranging from
1. Poison and Antidote
2. Hypochlorhydria and Hyperchlorhydria
3. Hypokalemia and Hyperkalemia
(b) Name the compounds which is used as
1. Anticoagulant 2. Expectorant 3. General anesthetic
4. Heamatinic 5. Fire extinguisher
05
(c) explain
1. Electrolyte used for replacement therapy
2. Essential ions
05
Q. six (a) Write Preparation of subsequent
1. Sodium thiosulphate 2. Sodium hydroxide
3. Calcium gluconate
06
(b) provide preparation of 5% w/v aqueous solution of iodine. provide the
reasons for the reagents used in preparation.
05
(c) Enlist the sources of the impurities in Pharmaceuticals and explain
the manufacturing hazards as source of impurity.
05
Q.7
(a) elaborate Radiopharmaceuticals ? provide uses of Iron [59Fe], Na 131I
and Cynocobalamine [ 57Co].
06
(b) Write a note on purified water and water for injection 05
(c) elaborate ideal requirement of antacids. provide preparation and uses of
any 1 antacid.
05

Earning:   Approval pending.