Gujarat Technological University 2010 B.Pharm Pharmaceutics I - Question Paper

Q.1 (a) Comment: Viscosity of slurry is an important factor in rate of filtration. 02
(b) explain the different mechanisms of filtration process. 04
(c) define rotary drum filter with diagram. 05

Q.2 (a) Explain: Centrifugal effect with formula. 02
(b) Write note on Metafilter. 04
(c) define contineous centrifuge with diagram. 05
(d) explain the principle of tubular bowl centrifuge with diagram. 05
Q.3 (a) Comment: Evaporation under decreased pressure should be used with caution. 02
(b) explain Duhring's rule and Raoult's legal regulations. 04
(c) define short tube evaporator with diagram. 05
(d) explain principle, advantages and disadvantages of film evaporators. 05
Q.4 (a) Explain: HETP and HTU. 02
(b) Differentiate: Evaporation and Distillation. 04
(c) define the steam distillation process. 05
(d) A 100 mole of liquid mixture containing 0.20 and 0.80 mole fraction of
components A and B, respectively was subjected to simple batch distillation. What
will be the liquid composition after eight mole of component A has been removed with
the vapors? presume aab as constant at 1.414.
05
Q.5 (a) Explain: CMC and EMC. 02
(b) define fluidized bad dryer with diagram. 04
(c) explain the process of spray drying. 05
(d) The wet solid containing three lb of water/lb of dry solid and with a density of 50 lb/ft3
was subjected to a drying using four ft long and three ft wide trays with wet solid depth of
2 inch. compute the number of trays needed to find 3000 lb of a product
containing one lb of water/lb of dry solid.
05
Q. six (a) Explain: Humidification and dehumidification. 02
(b) explain applications of humidity control in pharmacy. 04
(c) Draw a tagged diagram of humidifier with essential components. 05
(d) define compression refrigeration cycle with diagram. 05
Q. seven (a) Explain: Rectification and reflux ratio. 02
(b) Write note on azeotropic distillation. 04
(c) define mechanical hygrometers with diagram. 05
(d) explain principle, advantages and disadvantages of freeze drying. 05

Earning:   Approval pending.