Gujarat Technological University 2009 B.Pharm Pharmaceutics-II - Question Paper

Q.1 (a) Define: Size reduction. provide objectives of size reduction. discuss the mechanisms
of size reduction with a suitable diagram.
06
(b) discuss the construction, working, advantages, disadvantages and uses of Ball
mill with a suitable diagram. What is the importance of speed on size reduction
using a ball mill?
06
(c) Justify the subsequent statements giving suitable reasons.
1. Rate of feed is critical in size reduction by fluid energy mill.
2. The thickness of screen influences size reduction by hammer mill.
3. Moisture content plays an important role in the process of size reduction.
4. Sticky materials are difficult to size decrease.
04
Q.2 (a) describe the subsequent terms:
1. Crystal habit 2. Crystal lattice 3. Nucleation
4. Crystal hydrates 5. Amorphous compounds
05
(b) define the theory of crystallization explaining every stage with a
suitable diagram. discuss the term Polymorphism and its significance
06
(c) define the construction and working of Swenson walker crystallizer 05
Q.3 (a) describe mixing. discuss positive mixtures, negative mixtures and neutral mixtures
with suitable examples.
05
(b) discuss the mechanisms of solid-solid mixing. discuss the construction, working
and uses of planetary motion mixer.
06
(c) define the mixing devices used for liquid-liquid mixing? 05
Q.4 (a) Define: Extraction. Enumerate kinds of extraction processes.
Differentiate between: Maceration and Percolation
05
(b) Enumerate solvents used for extraction. define the properties
of water and ethanol as solvents for extraction
05
(c) discuss in detail the theory of extraction 06
Q.5 (a) elaborate the pharmacopeial standards for sieves used for size separation? 06
(b) Differentiate between: Elutriation and Sedimentation.
Write a brief note on cyclone separator.
05
(c) define the kinds of industrial hazards encountered in the operation of
processing plants.
05
Q. six (a) discuss the theory of compression 06
(b) define the Kawakita and Heckle equations and discuss their uses. 05
(c) define the pressure vacuum measurement systems in automatic process control
systems
05
Q.7 Write brief notes on the following: [Attempt any four] 16
(a) Meir's theory of super saturation
(b) Multiple extraction
(c) Energy requirements in size reduction
(d) Theory of solid-liquid mixing
(e) Methods of waste water treatment

Earning:   Approval pending.