Gujarat Technological University 2009 B.Pharm Pharm Chemistry II - Question Paper

Q.1 (a) describe any eight
1. Refractive index
2. Parachor
3. Dipole moment
4. Conductance
5. Partition Coefficient
6. Radioactivity
7. Optical activity
8. Ebullioscopic constant
9. Half life.
08
(b) What is meant by colligative property? discuss the freezing point
depression of solvent upon addition of nonvolatile solute.
05
(c) 15gm of unknown substance was dissolved in 1000ml of water at 25oC
was obtained to produce an osmotic pressure of 0.6 atm. What is molecular
weight of the substance? R = 0.0821 L atm /K
03
Q.2 Write a short note on any four
1. 1st legal regulations of thermodynamics
2. Fluorescence
3. Scintillation counter
4. Collision theory
5. Debye Huckel theory
16
Q.3 (a) describe viscosity and discuss what is meant by viscosity of liquid? Write
the units used to express the viscosity. explain the Pharmaceutical
application of viscosity.
06
(b) What is meant by surface tension of liquid? What causes its phenomenon?
explain the measurement of surface tension by drop formation method.
06
(c) explain different kind of solute- solvent interaction. 04
Q.4 (a) Compare properties of alpha, beta and gamma radiations. explain the
application of radiopharmaceuticals.
06
(b) discuss Langmuir and Gibb's adsorption isotherm 06
(c) State and discuss Beer-Lambert's legal regulations of Photometery. compute the
absorbance corresponding to ten and 100 % transmission.
04
Q.5 (a) discuss the order of reaction. Derive the formula for the 1st order
kinetics. provide illustration and characteristics of zero and 1st order
kinetics.
08
(b) discuss the difference ranging from the molecularity of reaction and order of
the reaction
04
(c) A solution of drug contained 500 unit per ml when prepared. It was
analyzed after 40 days and obtained to contains 300 units per ml. assuming
that decomposition is 1st order at what tie will the drug have
decomposed to 1 half of its original.
Q. 6
(a) provide cause
1. Degradation of the suspension of aspirin is stated to be apparent
zero order kinetic.
2. Benzoic acid forms dimmer in benzene but not in water.
3. Real solutions deviate from Roult's legal regulations.
4. On increasing pressure on water freezing point is lowered.
08
(b) describe specific optical rotation. provide the method of determining specific
optical rotation. Mention Pharmaceutical application of optical activity.
06
(c) discuss ion –induced dipole moment with illustration. 02
Q.7
(a) State the limitation of 1st legal regulations of thermodynamics. discuss the second
legal regulations of thermodynamics in different forms.
06
(b) discuss the phase diagram of 1 component and 3 phase system. 06
(c) discuss subsequent terms
1. Adiabatic process
2. Heat of Neutralization
3. Entropy
4. System

Earning:   Approval pending.