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Gujarat Technological University 2010-5th Sem B.Pharm BPharmacy Pharmaceutical Chemistry – V(Bio-Chemistry) - Question Paper

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Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth exam December 2010
Subject code: 250003
Subject Name: Pharmaceutical Chemistry – V(Bio-Chemistry)
Date: 15 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80
1. Attempt any 5 ques..
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) define the secondary structure of protein. 06
(b) explain the mechanism of enzyme inhibition. 05
(c) explain the transport mechanism across cell membrane. 05
Q.2 (a) What is glycolysis? provide their metabolic reaction with energetics. 06
(b) provide the structure and function of phospholipids. 05
(c) define the reaction of galactose metabolism. 05
Q.3 (a) Write about the mechanism of enzyme action. 06
(b) Write about the component and reaction of respiratory chain. 05
(c) explain the edman's techniques for determination of sequence of amino acids. 05
Q.4 (a) describe the vitamins. Write about the structure and coenzme activity of
riboflavin.
06
(b) Write about the significance of enzymes in diagnosis of disease. 05
(c) describe and classify carbohydrates with suitable examples. 05
Q.5 (a) Write shot note on followings.
1. Essential fatty acid. 2. Lipoproteins
06
(b) explain the importance of hormone in regulation of blood sugar level. 05
(c) Write the synthesis of ATP and provide their biological significance. 05
Q. six (a) Write about the reaction and energetics of citric acid cycle. 06
(b) describe the proteins. Classify them with suitable examples. 05
(c) discuss the glycogenolysis with metabolic reaction. 05
Q.7
(a)
Differentiate ranging from (i) epimers and anomers
(ii) saturated fatty acid and unsaturated fatty acid
06
(b) Write about the significance of folic acid and patothenic acid as co enzyme. 05
(c) Write about the metabolic reaction of pentose phosphate pathway. 05
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