Gujarat Technological University 2010-5th Sem B.Pharm BPharmacy Pharmacology - II - Question Paper

Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem- Vth exam December 2010
Subject code: 250005
Subject Name: Pharmacology - II
Date: 18 /12 /2010 Time: 02.30 pm – 05.30 pm
Instructions: Total Marks: 80
1. Attempt any 5 ques..
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) Write various stages of general anaesthesia. Write in brief about pre-anesthetic
medication.
06
(b) Write mechanism of action of benzodiazepines. 05
(c) Write note on Glutamate as a central neurotransmitter. 05
Q.2 (a) Classify antipsychotic drug. Write a note on atypical antipsychotic drugs. 06
(b) Write a note on Selective Serotonin Reuptake Inhibitors (SSRIs). 05
(c) Classify antiepileptic drugs according to mechanism of action. Write
pharmacokinetic and adverse effects of phenytoin.
05
Q.3 (a) Classify drugs used in Parkinsonism. Why Carbidopa is used in combination with
levodopa?
06
(b) Classify CNS stimulants and write a note on psychostimulants. 05
(c) Write a note on opioid agonists. 05
Q.4 (a) Classify Non-steroidal anti-inflammatory analgesics. Write a note on COX-2
inhibitors.
06
(b) Write note on Drug dependence. 05
(c) Write a note on Disulfiram 05
Q.5 (a) Classify antihypertensive agents. Write mechanism of action and therapeutic uses
of drug having adverse effect "dry cough"
06
(b) Drugs used in hypertensive emergencies and urgencies 05
(c) Write mechanism of action and pharmacological actions of cardiac glycosides 05
Q. six (a) Classify antiarrhythmic agents. Write mechanism of action and adverse effect of
Quinidine
06
(b) Write mechanism of action, adverse effect and therapeutic effect of nitrates. 05
(c) Write a note on fibrinolytic agents. 05
Q.7 (a) Classify diuretic agents. Write a note on thiazide diuretics 06
(b) Classify lipid lowering drugs. Write a note on HMG Co-A reductase inhibitors 05
(c) Write a note on :
1. Plasma expanders
2. Viral vectors used for gene therapy
05
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Attachment: gujarat-technological-university-2010-b-pharm-52720-1.zip

Earning:   Approval pending.