Gujarat Technological University 2010-3rd Sem B.Pharm BPharmacy Regular / Remedial Pharmaceutical Engineering II - Question Paper
Saturday, 20 July 2013 08:40Web
Seat No.: _____ Enrolment No.______
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharmacy Sem-III Regular / Remedial exam Dec. 2010
Subject code: 230002
Subject Name: Pharmaceutical Engineering II
Date: 13 /12 / 2010 Time: 10.30 am – 01.30 pm
Instructions: Total Marks: 80
1. Attempt any 5 ques..
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1 (a) What is supercritical fluid? Write theory of SCFs. 06
(b) Write note no RESS technology. 05
(c) discuss the pharmaceutical application of supercritical fluid
technology.
05
Q.2 (a) describe angle of repose and write methods for measurement of angle
of repose.
06
(b) Write note on factors affecting powder flow. 05
(c) describe Carr's index and hausner ratio with their pharmacopoeial
specification.
05
Q.3 (a) What is control chart? discuss the elements of control chart. 06
(b) provide a brief account on kinds of control chart. 05
(c) Highlight the pharmaceutical application of control chart. 05
Q.4 (a) discuss the importance of content uniformity and provide requirements
of regulatory agencies.
06
(b) Write sampling techniques for content uniformity. 05
(c) discuss statistical treatment for finding content uniformity. 05
Q.5 (a) discuss the factors affecting pellets properties. 06
(b) Write the process and equipment used for hot-melt extrusion. 05
(c) provide pharmaceutical application of Extrusion. 05
Q. six (a) discuss solid dispersion and inclusion complexes in detail. 06
(b) discuss the role of MCC in pelletization. 05
(c) discuss the working principle of ram extruder with well tagged
diagram.
05
Q.7 (a) discuss GAS (Gas antisolvent Recrystallization) in detail. 06
(b) discuss the cold extrusion. 05
(c) What is Eudragit? provide its role in melt extrusion. 05
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