Osmania University (OU) 2009-2nd Year B.Pharm .II SEMESTER (MAIN) ,IL/ (pharmaceutical bio chemistry) - Question Paper

CODE NO 1013
FACULTY OF TECHNOLOGY
b pharm.II year II semester (main) examination,April/may 2009
PHARMACEUTICAL BIO CHEMISTRY
time three hours max marks 70
ans all ques..
all ques. carry equal marks.

1 (a) (i) explain in detail biochemical organization of the cell.[marks 10]
(ii) write short notes on active transport.[marks 4]
OR
(b) (ii) enumerate the biological significance of ATP.[marks 8]
(ii) write a note on energy rich compounds.[marks 6]


2 (a) (i) discuss the process of glycolysis.[marks 10]
(ii) mention the clinical applications of enzymes.[marks 4]
OR
(b) (i)discuss the factors effecting enzyme action.[marks 10]
(ii)explain glycogen synthesis.[marks 4]

3 (a) (i) define the bio synthesis of saturated fatty acids.[marks 8]
(ii) write a note on synthesis of ketone bodies.[marks 6]
OR
(b) (i)explain E-oxidation of palmitic acid and add a note on its energetics.[marks 8]
(ii) provide an account on phospholipids.[marks 6]


4 (a) (i) discuss general metabolic pathways of amino acids.[marks 10]
(ii) write short notes on nitrogen balance.[marks 4]
OR
(b) (i) define the bio synthesis of DNA[marks 10]
(ii) discuss about recombinant DNA[marks 4]


5 (a) write principles involve and methods used in qualitative and quantitative analysis of subsequent in blood (i) glucose. (ii) albumin.[marks 7+7]
OR
(b) write short notes on :
(i) role of cyclic AMP in enzyme activation[marks 7]
(ii) feed back inhibition[marks 7]

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Earning:   Approval pending.