Osmania University (OU) 2011-2nd Sem B.Pharm 4th yrmake-up (subject- Pharmacoinformatics) - Question Paper

Code No. 6535

FACULTY OF TECHNOLOGY

B. Pharmacy SV - Year li~Semester (Make-up) Examination, August 2011

Subject: Pharmacoinformatics Time : 3 Hours    Max. Marks : 70

Note : Answer aft questions. All questions carry equal marks.

1 .(a) What is a database? Write about different types of databases.

OR

(b) What is data mining? How can it iead to knowledge discovery in database?

2.(a) Describe in detail the use of Hidden Markov Models in Bioinformatics.

OR

(b) Describe in detail about the algorithms for nucleic acid sequence alignment along with examples.

3.(a) Explain in detail about the critical steps involved in evaluation of drug information.

OR

(b) Write in detail about pharmacy automation and automated medication dosage.

4.(a) Discuss about homology algorithms for proteins and nucleic acids.

OR

(b) Describe in detail about DNA and protein databases and their applications.

5.(a) What is structure-activity relationship of drugs? How does it differ from quantitative structu re-activity relationship analysis?

OR

(b) What are the various factors that affect bioactivity of drugs? Write it detail. Write about theories of drug action and drug receptor interactions.

Attachment: osmania-university--ou--2011-b-pharm-48155-1.jpg

Earning:   Approval pending.