Osmania University (OU) 2012-2nd Year B.Pharm macy IV semester PHARMCEUTICAL BIOTECHNOLOGY - Question Paper

Faculty of Pharmacy
B.Pharmacy IV Year II semester (Main) exam April/may 2012
PHARMACEUTICAL BIOTECHNOLOGY
Time: three Hours Max.Marks:70
Note : ans all ques.
All ques. carry equal marks
1. a) describe r DNA technology. define the importance of the restriction endonucleases, DNA Ligases and cloning stratergies in r DNA technology ( 14)
OR
b) provide an account of the production of insulin by rDNA technology (14).

2. a) provide an account of microbiological assay of vitamine B12 (14)
OR
b) (i) Draw the neat diagram of Aerobic fermentor and discuss its parts.
(ii) Write the fermentative production of any 1 antibiotic (7+7)

3. a) provide an account of :
(i)Viral Vaccines
(ii) Immuno diagnostics (7+7)
OR
b) provide a account of the preparation,purification and standardization of any 1 antitoxin (7)

4. a) provide an account of the preparation of :
(i) Dried human plasama
(ii) Human fibrin foam (7+7)
OR
(b) (i) elaborate the idela requirements of plasma substitute?
(ii) provide a detailed account of production of dextran. (7+7)

5. (a) provide detailed accounts of microbial biotransformation of steroids. (14)
OR
(b) provide an account of hybridoma technology in the production of monoclonal antibodies
( 14)

Earning:   Approval pending.