Jawaharlal Nehru Technological University Hyderabad 2010-2nd Sem M.Tech Biotechnology Regular s tember, ADVANCED IMMUNOLOGY AND IMMUNOTECHNOLOGY - Question Paper

Code No: D0305
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
M.Tech II - Semester Regular exams September, 2010
ADVANCED IMMUNOLOGY AND IMMUNOTECHNOLOGY
(BIOTECHNOLOGY)
Time: 3hours Max. Marks:60
ans any 5 ques.
All ques. carry equal marks
- - -

1. How does the immune system learn to differentiate ranging from self and non-self?
discuss the mechanism involved.

2. How does the immune system recognize foreign bodies and eliminate them? What
implication does this have on allograft transplant rejection?

3. discuss the mechanism at work in Cross-presentation and its role in immune
tolerance and immunity.

4. While we are all vaccinated for different lethal pathogens in childhood, how would
you discuss the relationship ranging from the ability of our system to recognize the
pathogen despite the gap ranging from vaccination and infection?

5. What do you understand by Hybridoma technology? discuss the different steps
involved in creating a hybridoma cell line using an example.

6. Differentiate ranging from polyclonal and monoclonal antibodies, discuss the methods
used in their production.

7. define the role of Liposomes in vaccination delivery. explain about their
mechanism of action and their limitations.

8. "A major unsolved challenge in adjuvant development is how to achieve a potent
adjuvant effect while avoiding reactogenicity or toxicity"- discuss the statement.

Earning:   Approval pending.