Jawaharlal Nehru Technological University Hyderabad 2010-2nd Sem M.Tech Biotechnology Regular s tember, BIOINFORMATICS - Question Paper

Code No: B0308 / D0307
JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY HYDERABAD
M.Tech II - Semester Regular exams September, 2010
BIOINFORMATICS
(BIOTECHNOLOGY)
Time: 3hours Max.Marks:60
ans any 5 ques.
All ques. carry equal marks
- - -

1. describe Bioinformatics? elaborate the research areas in Bioinformatics and role of
Bioinformatics and its applications in the field of Biotechnology?

2. Write in detail about shotgun sequencing method.

3. elaborate the heuristic methods employed for database searching? discuss Gapped
Blast. elaborate the applications of such database searches?

4. What is meant by sequence alignment? discuss about various techniques
employed for Pair wise alignment?

5. Write an essay on conformational analysis and forces that determine protein
structure.

6. discuss the standard process that is used in homology modeling?

7. discuss in detail about the steps in drug designing project.

8. Write short notes on the subsequent
a. Micro array Analysis in Drug Discovery
b. PROTEIN-DOCKING.

Earning:   Approval pending.