Jawaharlal Nehru Technological University Hyderabad 2010-2nd Sem B.Pharm iiibpharmacyregular s chemistry of natural drugs - Question Paper

JNTU HYDERABAD III. B. PHARMACY II SEMESTER REGULAR exams MAY 2010 CHEMISTRY OF NATURAL DRUGS

1.(a) How will you differentiate the subsequent by hydrolysis, discuss with
chemical reaction and structure.
i) Atropine
ii) Hyoscyamine
iii) Hyosine
(b) Differentiate tropine and pseudotropine.
2. Classify ergot alkaloids and provide structures, hydrolytic products and therapeutic uses of any 4 ergot alkaloids?
3. discuss the subsequent.
a. Isoprene rule
b.Gem-dialkyl rule
c.Ozonolysis of terpenes
d.Stereochemistry of citral
4. Convert the subsequent
a. Cavone to cavacrol
b. Menthol to thymol
c. Borneol to camphor
d. Camphor to borneol
5. Write on the subsequent
a. Numbering of Bile acids, cholesterol, estrone, diels hydrocarbon
b. Synthesis of progesterone from diosgenin and cholesterol
6. Write detailed note on cardiac glycosides and mention MOA, toxicity and
thearapeutic uses?
7. Classify steroidal hormones and provide brief note on the subsequent
a. Contraceptive agents
b. Inter-conversion of estrogens
8. Write an account on
a) Insulin b) Cortisone c) Glucagon d) Thyroxine

Earning:   Approval pending.