Rajiv Gandhi University of Health Sciences 2007 M.B.B.S-PHARMACOLOGY - - I (Revised Scheme 2)-PHASE - II - Question Paper

Rajiv Gandhi University of Health Sciences
M.B.B.S. PHASE - II Degree exam - February 2007
Time: three Hrs. [Max. Marks: 100]
PHARMACOLOGY - PAPER I (Revised Scheme 2)
QP Code: 1085
By Dr.Bhargava, JJMMC, Davangere
&
Dr.Nandish, BMC
Q Paper Courtesy: Dr. Singi Yatiraj
LONG ESSAY two X 10 = 20 Marks
1. Classify Antihypertensive drugs with examples for every group. discuss mechanism of
action, therapeutic uses and adverse effects of Angiotensin Converting enzyme (ACE)
inhibitors.
2. Classify Anticholinergic drugs with examples for every group. define pharmacological
actions, therapeutic uses and adverse effects of Atropine.
SHORT ESSAY 10 X five = 50 Marks
3. discuss protein binding of drugs with suitable examples. provide its clinical importance.
4. discuss basis for use of Nitroglycerine in Angina pectoris. Enumerate routes of
administration and unwanted effects.
5. Lignocaine â mechanism of action, indications for use and different routes of
administration and 2 side effects.
6. Carbamazepine â indicat ions for use and side effects.
7. Drug - Drug antagonism â Define, mention the kinds and mechanisms with
examples.
8. elaborate Fibrinolytic agents? provide examples â mechanisms and their uses.
9. Mention Beta2 agonists and write their therapeutic uses and side effects.
10. Mention plasminogen activators with their therapeutic indications and side effects.
11. elaborate atypical antipsychotics? Mention examples of advantages over the older ones.
12. Mention organophosphorous compounds. How do you treat organophosphorous
poisoning?
SHORT ANSWERS 10 X three = 30 Marks
13. State the basis for the use of Pilocarpine in glaucoma. Mention 2 adverse
effects.
14. State reasons â Chlorpromazine is an antiemetic but is not useful in motion
sickness.
15. State reasons â Dopamine is preferred to noradrenaline in circulatory failure.
16. Mention advantages and disadvantages of sublingual route of drug
administration.
17. What is neuroleptanalgesia? elaborate the drugs used for it?
18. What is Atracurium? How is it eliminated from the body? Write indications for its
use.
19. Methadone â discuss the basis for its use in heroin dependence.
20. Malignant Hyperthermia. Mention the drugs causing this condition and outline the
treatment.
21. Mention 2 COMT (Catechol â O â Methyl transferase) inhibitors in the
treatment of Alzheimerâs disease. Mention 2 adverse effects.
22. Orphan drugs â describe & provide examples.

Earning:   Approval pending.