Dr MGR Educational and Research Institute 2011 M.B.B.S SECOND Revised (Non-Semester) Regulations III - GENERAL PATHOLOGY AND HAEMATOLOGY QPCode : 524063 - Question Paper

February 2011
SECOND M.B.B.S. DEGREE exam.
Revised (Non-Semester) Regulations
Paper III - GENERAL PATHOLOGY AND HAEMATOLOGY
Q. P. Code : 524063
Time : 3 hours Maximum: 100 Marks
I. Essay ques. : (2 x 15 = 30)

1. describe Necrosis. Name the various kinds of necrosis. explain in detail with examples the various kinds of necrosis. Differentiate ranging from Necrosis and Apoptosis.

2. A 70 year old women admitted with worsening anemia and pathological fracture of the Humerus had an ESR of 120mm in one hour. Her peripheral smear showed increased rouleaux formation. Xray of skull showed multiple punched out osteolytic lesions.
a. What is the most probable diagnosis? Write briefly on the etiopathogenesis
of this disease.
b. define the Bone Marrow modifications in this disease.
c. Enumerate the common laboratory investigations for this disease.
d. Enlist the complications of this disease.

II. Write Short notes on : (10 x five = 50)

1. Role of Arachidonic Metabolites in inflammation.

2. Pathogenesis of Septic Shock.

3. Tumour Metastasis.

4. Mitochondrial Inheritance.

5. Etiopathogenesis of Cystic Fibrosis.

6. Anemia of Chronic Disease.

7. FAB classification of Acute Leukemia.

8. Idiopathic Thrombocytopenic purpura.

9. Transfusion Reaction.

10. Hematocrit.

III. Short ans ques. : (10 x two = 20)

1. provide 4 examples for pathological calcification.

2. provide 4 examples for Metaplasia.

3. Mention 2 differences ranging from exudates and transudate.

4. Mention 2 renal modifications in SLE.

5. provide 2 examples for trace elements and their deficiency states.

6. provide 4 causes for iron deficiency anaemia.

7. Mention 2 important marrow modifications in B12 deficiency.

8. 2 characteristic difference ranging from Myeloblasts and Lymphoblasts.

9. Mention 2 pathognomonic features of Hairy cell leukemia.

10. Mention 4 applications of reticulocyte count.

Earning:   Approval pending.