Dr MGR Educational and Research Institute 2011 M.B.B.S SECOND Revised %28Non-Semester%29 Regulations V - PHARMACOLOGY - I Q.PCode%3A 524065 - Question Paper

August 2011
SECOND M.B.B.S. DEGREE exam.
Revised (Non-Semester) Regulations
Paper V - PHARMACOLOGY - I
Q.P. Code: 524065
Time : 3 hours Maximum : 100 marks
I. Essay ques. : (2 x 15 = 30)

1. (i) Enumerate the different sedative and hypnotic drugs.
(ii) explain the mechanism of action, uses and adverse effects of benzodiazepines. (iii) Briefly explain the management of acute barbiturate poisoning.

2.
(i) Classify anticholinersterases
(ii) explain the mechanism of action and indications of reversible anti-cholisterases (iii) Outline the management of acute organophosphorous poisoning.

II. Write Short notes on : (10 x five = 50)

1. Mydriatics.

2. Drugs used in prophylaxis of migraine.

3. Receptor antagonism of drugs.

4. Sublingual route of administration.

5. Blood-Brain barrier.

6. Therapeutic uses of loop diuretics.

7. Parenteral iron therapy.

8. Epsilon amino-caproic acid.

9. Therapeutic uses of prostaglandin analogues.

10. Uricosuric agents.

III. Short ans ques. : (10 x two = 20)

1. Mechanism of action of Disulfiram.

2. What is potentiation of drug action? Mention two examples?

3. What is Eutetic mixture? Mention its indications.

4. Mention two uses, two advantages and two disadvantages of thiopentone sodium.

5. What is 1st order kinetics?

6. What is fixed dose combination? provide two examples

7. Mention two selective Cox-2 inhibitors. elaborate the advantages?

8. elaborate antitussives? provide two examples.

9. Mention two thiazide diuretics. Mention two uses of thiazides.

10. What is the mechanism of action and uses of Montelukast ?

Earning:   Approval pending.