Dr MGR Educational and Research Institute 2010 M.B.B.S SECOND Revised (Non-Semester) Regulations V - PHARMACOLOGY - I QPCode : 524065 - Question Paper

August 2010
SECOND M.B.B.S. DEGREE exam.
Revised (Non-Semester) Regulations
Paper V - PHARMACOLOGY - I
Q. P. Code : 524065
Time : 3 hours Maximum: 100 Marks
I. Essay ques. : (2 x 15 = 30)

1. i) Classify antiepileptic drugs with examples for every group.
ii) define mechanism of action, adverse effects and therapeutic
indications of Diphenyl hydantoin.
iii) Role of Topiramate in epileptic patients.

2. i) describe drug and dose.
ii) Factors modifying drug action.

II. Write Short notes on : (10 x five = 50)

1. Classification and therapeutic uses of a (Alpha) - blockers.

2. Pharmacotherapy of migraine.

3. Thiazide diuretics - Mechanism of action, adverse effects and uses.

4. Drug therapy of chronic gout.

5. Heparin - mechanism of action, adverse effects and indications.

6. Therapeutic uses of prostaglandins.

7. Treatment of organophosphorus poisoning.

8. Drugs to be avoided in elderly and their safer options.

9. Treatment of Myocardial infarction.

10. Enumerate statins. Write about mechanism of action and indications of
statins.

III. Short ans ques. : (10 x two = 20)

1. Mention 4 drugs bound to plasma albumin.

2. What is Rupatadine? Mention 1 indication for it.

3. Mention 2 Leukotriene antagonists used in bronchial asthma.

4. What is fomepizole? Mention 1 indication for it.

5. Mention any 4 preanaesthetic medicants.

6. Mention 4 angiotensin receptor blockers.

7. Drugs used in anaphylactic shock.

8. Mention 2 non benzodiazepine hypnotics.

9. Mention 2 selective dopamine agonists used in Parkinson's disease.

10. provide 2 examples for physiological functional antagonism.

Earning:   Approval pending.