Dr MGR Educational and Research Institute 2010 M.B.B.S SECOND Revised (Non-Semester) Regulations VI - PHARMACOLOGY - II QPCode : 524066 - Question Paper

August 2010
SECOND M.B.B.S. DEGREE exam.
Revised (Non-Semester) Regulations
Paper VI - PHARMACOLOGY - II
Q. P. Code : 524066
Time : 3 hours Maximum: 100 Marks
I. Essay ques. : (2 x 15 = 30)

1. i) Enumerate the antimetabolites used in neoplastic diseases.
ii) Write the mechanism of action and therapeutic uses of Methotrexate. iii) Add a note on treatment of Methotrexate toxicity.

2. i) Classify antithyroid agents.
ii) Mention the pharmacological actions and therapeutic uses of
carbimazole.
iii) Add a note on radioactive iodine.

II. Write Short notes on : (10 x five = 50)

1. INH.

2. Management of cerebral malaria.

3. Ketoconazole.

4. Treatment of scabies

5. Management of diabetic ketoacidosis.

6. Selective Estrogen Receptor Modulators (SERMS).

7. Newer insulin preparations.

8. Low molecular weight heparins.

9. Vitamin - D.

10. British Anti-Lewisite (BAL).

III. Short ans ques. : (10 x two = 20)

1. Rationale for giving chloroquine and primaquine in acute vivax malaria.

2. Rationale for using clofazimine in lepra reaction.

3. 2 Uses and 2 adverse effects of metronidazole.

4. Why ciprofloxacin is contraindicated in children less than eight yrs of age?

5. 2 indications of albendazole.

6. Sulfonylureas are not effective in kind I diabetes mellitus.

7. What is grey baby syndrome?

8. Rationale for using Bromocriptine in acromegaly

9. Ranitidine is preferred to cimetidine in peptic ulcer.

10. Cisplatin.

Earning:   Approval pending.