Dr MGR Educational and Research Institute 2010 M.B.B.S FIRST Revised (Non-Semester) Regulations VI - BIOCHEMISTRY - II QPCode : 524056 - Question Paper

February 2010
FIRST M.B.B.S. DEGREE exam.
Revised (Non-Semester) Regulations
Paper VI - BIOCHEMISTRY - II
Q. P. Code : 524056
Time : 3 hours Maximum: 100 Marks

I. Essay ques. : (2 x 15 = 30)

1. explain about nucleic acids under subsequent headings:
a) Types b) Functions c) Components
d) Char gaffs rule of DNA composition
e) various forms of DNA double helix and
f) Differences ranging from DNA and RNA.

2. define the steps of s-adenosyl methionine cycle. discuss the term
transmethylation with 5 suitable examples.

II. Write Short notes on : (10 x five = 50)

1. provide an account of the formation of specialized products from glycine.

2. discuss the term transamination and its salient features.

3. Polymerase chain reaction and its applications.

4. Blotting techniques.

5. Gene therapy.

6. Write an account of salvage pathway in purine nucleotide synthesis. Add a note on Lesch - Nyhan syndrome.

7. Post translational modification.

8. elaborate porphyrias? define any 3 porphyrias in detail.

9. provide an account of water distribution and its balance in the body.

10. elaborate isotopes? elaborate its applications in biochemistry?

III. Short ans ques. : (10 x two = 20)

1. Phenyl keton uria.

2. Structure of t-RNA.

3. Okazaki pieces.

4. Differences ranging from CPSI and CPS II.

5. Metabolic role of magnesium.

6. Anion Gap.

7. Rotheras test.

8. Gout.

9. Flurosis.

10. Vanden Berg test.

Earning:   Approval pending.