University of Hyderabad (UoH) 2011 M.Sc BioTechnology Entrance for (Animal ) - exam paper
Department of Animal Sciences ENTRANCE EXAMINATION, JUNE 2011 M. Sc Animal Biotechnology Time: 2 hours Maximum Marks: 100
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1. The complete aerobic respiration of glucose produces
A) Lactate and carbon dioxide B) Water and oxygen
C) Water and carbon dioxide D) Lactate and oxygen
2. The drug which selectively inhibits DNA polymerases and blocks DNA synthesis-
A) a-Amanitin B) Aphidicolin
C) Actinomycln D D) Rifampicln
3. The fetal placenta and umbilical cord are formed from the
A) Chorion & amnion B) Chorion & endometrium
C) Chorion & yolk sac D) Chorion & allantois
4. Gram positive cells have
A) A second outer membrane that B) Multiple layer of peptidoglycan that helps to retain the crystal violet help to retain the crystal violet stain stain
C) A thick capsule that traps the D) A periplasmic space that traps the crystal violet stain crystal violet stain
5. Which of the following techniques are used for the analysis of restriction fragment length polymorphisms?
A) Electrophoresis & chromatography B) Restriction enzyme digestion &
chromatography
C) Methylation & Restriction enzyme D) Restriction enzyme digestion & digestion electrophoresis
6. Lipid A stimulates the synthesis of which factor?
A) Transforming growth factor (TGF) B) Platelet derived growth factor (PDGF)
C) Epidermal growth factor (EGF) D) Tumor necrosis factor (TNF)
7. The only living echinoderms which are fully sessile -
A) Sea lilies B) Sea cucumbers
C) Sand dollars D) Sea urchins
8. Which one of the following agent is commonly used for determining the N-terminal amino acid of a polypeptide?
A) Trypsin B) Cyanogen bromide
C) Phenyl isothiocyanate D) Aminopeptidase
9. The Michaelis-Menten constant Km is
A) Numerically equal to /? Vmax B) Independent of pH
C) Dependent on the enzyme D) Numerically equal to substrate concentration concentration that gives half-
maximal velocity
10. The unfertilized eggs laid by queen bee develop into
A) Queens B) Workers
C) Drones D) Hermaphrodite
11. The chromosome composition seen in different syndromes is given below. Identify the pair that is mismatched.
A) Turners syndrome - 45 (AA+XO) B) Down's syndrome - 47: Trisomy of
21st chromosome
C) Kleinfelter's syndrome -47 D) Patau's syndrome - 45: Monosomy
(AA+XXY) of 13th chromosome
12. Which one of the following sequences shows the correct hierarchy of classification, going from the most inclusive to the least inclusive?
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A) Kingdom, phylum, order, class, B) family, genus, species C) Kingdom, order, phylum, class, D) family, genus, species |
Kingdom, phylum, class, order, family, genus, species Kingdom, class, order, family, genus, species |
13. Silicon is a
A) Insulator
C) Semiconductor
B) Conductor D) Non-conductor
14. Which of the following disease is not caused by bacteria?
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A) Plague B) Cholera
C) Yellow fever D) Tuberculosis
15. If an affected male has all affected daughters, but no affected sons, the trait is likely to be an
A) X-llnked dominant trait B) Autosomal recessive trait
C) Autosomal dominant trait D) X-linked recessive trait
16. The molarity of a solution containing 5.844 gram NaCI in 100 mL is
A) 0.01 M B) 0.1 M
C) 1 M D) 10 M
17. The phylum of plants that includes mosses is
A) Anthocerophyta B) Bryophyta
C) Lycophyta D) Pterophyta
18. The premature aging syndrome caused due to the mutation in DNA repair enzymes is
A) Hutchinson-Gilfcrd Progeria B) Dementia
C) Aphasia D) Schizophrenia
19. Which one of the following pairs are analogous structures?
A) The front leg of horse and a B) The front leg of frog and a bat wing human arm
C) The front flipper of a whale and a D) The wings of bird and butterfly human arm wings
20. Hydrolysis of one ATP molecule to AOP releases_calories of energy.
A) 730 B) 7,300
C) 68,600 D) 73,000
21. Which one of the following DNA duplex has highest melting temperature?
A) 5' ATGGCTCGT 3' B) 5' GGCTGGAGA 3'
3' TACCGAGCA 5' 3' CCGACCTCT 5'
C) 5' ATGGGCCCTG 3' D) 5' ATGATACTG 3'
3' TACCCGGGAC 5' 3' TACTATGAC 5'
22. Receptors for which of the following hormones are found in the cytoplasm of responsive cells?
A) Thyroid hormone and insulin B) Glucagon and estrogen
C) Insulin and estrogen D) Thyroid hormone and estrogen
23. The cooking time for food is reduced in a pressure cooker because
A) Heat is more evenly distributed in B) Boiling point of the water involved in the cooking space cooking is increased
C) The higher pressure Inside the D) Boiling point of the water involved in cooker pulverizes the food material cooking is decreased
24. The animals that are genetically constructed to differ at one particular locus are called as
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A) Chimeric B) Congenic
C) Hybrid D) Transgenic'
25. Sequencing and analysis of rRNA has divided the living world into three domains called
A) Bacteria, archaea & eukarya B) Archaea, eukarya & virus
C) Fungi, plants and animals D) Bacteria, archaea & plants
26. A process in which movement of a molecule across the membrane down Its concentration gradient is coupled to the movement of a second molecule up its concentration gradient and across the membrane in opposite direction is called *
A) Active transport B) Uniport
C) Antiport D) Symport
27. The matrix of mitochondria contains
A) A high concentration of glucose
B) FADH2
D) Glycogen
B) Nephridia
D) Malpighian tubules
C) Citric acid cycle intermediates
for excretion
28. Planarian use_
A) Flame cells
C) Uriniferous tubules
29. The occurrence of tetratype in the acetomycete fungi is possible only if the crossing over occurred during the
A) Four-strand stage B) G1 phase
C) Two-strand stage D) S phase
30. In mammals, the diaphragm separates the
ti) Thoracic cavity from the pericardial Peritoneal cavity from the thoracic
cavity cavity
) Peritoneal cavity from pericardial J>) Thoracic cavity from the pelvic cavity cavity
31. Which one of the following metabolites is not directly produced in the hexose monophosphate shunt pathway?
Dihydroxyacetone phosphate D) Gluconolactone-6-phosphate
B) Cristae of mitochondria D) Outer mitochondrial membrane
A) Fructose-6-phosphate C) Erythrose-4-phosphate
32. Cytochromes are found in
A) Inner mitochondrial membrane
C) Matrix of mitochondria
33. Tapeworms attach to the digestive lining of the host by means of their
A) Proglottid B) Stylete
C) Mastax D) Scolex
34. Iff the paternal chromosomes have alleles A, B, c and the maternal chromosomes have a, b, C - then the chromosomes that are not a product off crossing over are -
A) A B C and a b c B) A b C and a B c
C) A b c and a B C D) A B c and a b C
35. Nondisjunction involving the X chromosomes may occur during oogenesis and produce two kinds off eggs. Iff normal sperms fertilize these two types, which off the following pairs of genotypes are possible?
A) XX and XY B) XXY and XO
C) XXY and YO D) XX and XO
36. Methionyl-transffer RNA is used for initiation off protein synthesis by which off the following?
A) Chloroplast B) Fukaryotic cytoplasmic ribosomes
C) Bacterial ribosomes D) Eukaryotic mitochondrial ribosomes
37. Which component in the viral envelope attaches the human deficiency virus (HIV) to host cells?
A) gp41 B) pl8
C) gpl20 D) p24
38. Which one off the following could be used to distinguish between an aldose and a ketose?
A) Br2 water B) Tollen's reagent
C) Fehling's reagent D) Feulgen's reagent
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39. Common method used for determination of the three dimensional structure off proteins is | ||||||||||||||||||||
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41. Iff a phosphodiester bond in one strand of double stranded circular DNA is broken, the DNA is said to be
A) Digested B) Linearized
C) Cleaved D) Nicked
42. The first virus to be puriffied was
A) Influenza virus B) Tobacco Mosaic virus
C) Polio virus D) Smallpox
43. The amino acid leucine has the following side chain.
A) CH3-CH(CH)2- B) (ch3)2-ch - ch2 -
C) CH3 - CH (OH) - D) CH3 - CH2 - CH (CH3)-
44. Which one of the following Is WOT a part of the Immune system?
A) Spleen B) Thymus
C) Tonsil D) Pancreas
45. Liebermann's reaction is used for detection of
A) aniline B) benzoic acid
C) nitrobenzene D) phenol
46. When an animal cell is placed in 0.5 M sucrose solution, its volume does not alter. When the same cell is transferred to a 0.5 M NaCI solution, the volume of the cell will -
A) Remain unchanged B) Decrease
C) Increase D) Increase and then decrease
47. Which one of the following is mismatched?
A) Matrix - extracellular material in B) Cardiac muscle cells - multiple nuclei connective tissue
C) Adipose cells - found in loose D) Ligaments - bind muscles to bone connective tissue
48. The nucleic acid which Is highly modified by extensive methylation after synthesis is
A) hnRNA B) mRNA
C) tRNA D) rRNA
49. Which one of the following is an acidic amino acid?
A) Aspartic acid B) Isoleucine
C) Lysine D) Proline
50. Genetic recombination in bacteria occurs through the transfer of
A) Pili B) Plasmids
C) Endospores D) Gametes
51. The second messenger which plays a crucial role in regulating the synthesis and breakdown of glycogen in liver and muscle cells is
A) CAMP B) cGMP
C) DAG D) IP3
52. What blocks myosin from binding to actin, when the muscle is at rest?
A) Acetylcholine B) ATP
C) Troponin D) Tropomyosin
53. Which one of the following is not a cancer drug?
A) Isoniazid B) Cisplatin
C) Methotrexate D) Daunorubicin
54. Isotypes defer to variation in the
A) Light chain variable region B) Light chain constant region
C) Heavy chain variable region D) Heavy chain constant region
55. When chromosome breakage occurs and the broken segment rotates by 180 degrees before reunion, the resulting chromosome aberration is known as
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A) Insertion B) Translocation
C) Inversion D) Frame shift
56. A common method for separating cell organelles and insoluble material from soluble proteins is
A) Filtration B) Column chromatography
C) Polyacrylamide gel electrophoresis D) Differential centrifugation
57. Cystic fibrosis is caused by _mutation.
A) Autosomal recessive B) Autosomal dominant
C) Sex-linked recessive D) Sex-linked dominant
58. In sensory neurons, stimuli are conducted through
A) Axons B) Dendrites
C) Cell body D) Myelin sheath
59. According to molecular definition of a gene, which one of the following is not a part of eukaryotic gene?
A) Promoter B) Poly (A) tail
C) Enhancer D) Polyadenylation signal
60. At room temperature formaldehyde changes into
A) Trioxane B) Paraldehyde
C) Acetaldehyde D) Acetic acid
61. Which one of the following is part of the gynoecium?
A) Filament B) Carpel
C) Stamen D) Sepal
62. The major class of insoluble fibrous protein present in the extracellular matrix and in connective tissue is
A) Actin B) Cadherin
C) Collagen D) Fibronectin
63. The following method helps in determining the genotype of an individual for a
particular trait
A) Test cross B) Back cross
C) Monohybrid cross D) Dihybrid cross
64. The rhythmic beating of the heart is initiated by the
A) Purkinje fibers B) Bundle of His
C) Atrioventricular node D) Sinoatrial node
65. Which one of the following is an innate immune cell type?
B lymphocyte T lymphocyte
C) Macrophage NKT cells
66. Which one of the following is not characteristic of members of the plant kingdom?
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A) Carotenoids B) Chlorophyll c
C) Chlorophyll a D) Chlorophyll b
67. Releasing hormones (TRH, GnRH etc.) in higher animals are synthesized and secreted by
A) Adenohypophysis B) Neurohypophysis
C) Hypothalamus D) Pars-intermedia
68. The neurotransmitter at the neuromuscular junction is-
A) Dopamine B) Serotonin
C) Acetyl choline D) Epinephrine
69. Which one of the following is not a primary alcohol?
A) Methanol B) Ethanol
C) Benzyl alcohol D) Isopropyl alcohol
70. Green algae, recently been investigated as food source in several nations is
A) \/olvox B) Chlorella
C) Chlamydomonas D) Pseudomonas
71. The virus commonly used for the management of insect pests as well as a vector for production of recombinant proteins is
A) Retrovirus B) Adenovirus
C) Parvovirus D) Baculovirus
72. Two antagonistic hormones are-
A) MSH & TSH B) Calcitonin & Parathormone
C) ADH & GH D) Oxytocin & Prolactin
73. Which has the maximum percentage of Cl?
A) Neoprene B) PVC
C) BHC D) DDT
74. The inflammatory response includes all of the following except
A) Vessel constriction B) Temperature increase
C) Increased blood flow D) Phagocytic attack
75. Worlds natural gas reservoirs are primarily produced by
A) Anaerobic fungi B) Actinomyces
C) Primitive protists D) Archaebacteria
76. Components of animal cell cytoskeleton found in cilia and flagella that direct chromosomal movement during cell division are
A) Microtubules B) Microfilaments
C) Intermediary filaments D) Microtubules and microfilaments
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77. Solid C02 Is an example of A) Ionic crystal B) D) C) Covalent crystal 78. The following are epimers of glucose A) Galactose and fructose B) C) Mannose and fructose D) |
Metallic crystal Molecular crystal Mannose and galactose Sucrose and fructose |
79. Enzymes from the following organelle are involved in the oxidation of fatty acids, but the released energy is not used for ATP synthesis
A) Mitochondria B) Lysosomes
C) Peroxisomes D) Ribosomes
80. While most of the insects have four wings, the following have only two
A) Cockroach B) Housefly
C) Butterfly D) Honeybee
81. Enzyme produced in the kidney, which catalyzes the cleavage of angiotensinogen present in the blood-
A) Angiotensin B) Bradykinin
C) Kynurenine D) Renin
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82. Cerebellum regulates A) Body temperature C) Sleep-wake cycle |
B) Movement and balance D) Learning and memory |
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A) Enzymes C) DNA D) 83. If radioactive sulphur is added to culture medium of E. coli, the radioactive label after 48 hours will be localized in B) 84. Vertebrate lungs are derived from ) Ectoderm B) q ) Endoderm J) j 85. Glucokinase A) Is widely distributed in most of the B) mammalian tissues C) Is inhibited by glucose-6- D) phosphate |
RNA Phospholipid Epiderm Mesoderm Has high Km for glucose Catalyzes a reversible reaction |
86. Humans can digest starch and not cellulose. Both of them contain monomeric glucose units. Starch is digested due to specificity of the intestinal enzymes for
A) a l->4 linkage B) 3 l->4 linkage
C) a l->6 linkage D) P l->6 linkage
87. Drugs that prevent the formation of bacterial cell wall are
A) quinolones B) beta-lactams
C) tetracycline D) Aminoglycosides
88. Heat shock proteins, originally identified as proteins expressed in response to stress, also function as
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A) Protein kinase B) GTPase activating proteins
C) Proteases degrading ubiquitin- D) Molecular chaperones, which assist in de tagged proteins novo protein folding
89. When a lead storage battery is discharged
A) SO? is evolved B) Lead sulfate is consumed
C) Lead is formed D) Sulphuric acid is consumed
90. The genome of an organism contains 20% adenine residue. Which one of the following statement is correct?
A) G + C content is 20% B) G + C content is 40%
C) G + C content is 60% D) G + C content is 80%
91. If one mL of 0.01 M HCI is diluted to 100 mL at 25 C, what will be the pH of the resulting solution?
A) 2 B) 4
C) 5 D) 7
92. Which one of the following pathway is very active in the tissues involved in lipogenesis and nucleic acid biosynthesis?
A) Glycolysis B) TCA cycle
C) p oxidation D) HMP shunt pathway
93. Which one of the following is a human cell line?
A) CHO B) Hela
C) BHK-21 D) Sf-9
94. When a gasoline is given "octane number" 80, it means it contains
A) 80% octane B) 80% iso*octane
C) 20% iso-octane D) 20% benzene
95. The bacteria which utilize C02 as the sole carbon source and obtains energy by oxidation and reduction of inorganic substances are called as
A) Chemolithotrophs B) Photoautotrophs
C) Chemoheterotrophs D) Photoheterotrophs
96. Human albinism is caused by recessive gene 'a'. A child has albinism, although none of the parents are affected. What is the genotype of parents?
A) AA and AA B) Aa and AA
C) Aa and Aa D) Aa and aa
97. Viral replication within cells is inhibited by
A) IL-1 B) IL- 4
C) IFN*y D) TNF- a
98. In the mitochondrial genome, the stop codon is
A) AGA B) UGA
C) UUU D) UAA
99. Which one of the following is a polyatomic cation?
u
A) Mg2+ B) NH/
C) Cu2+ D) OH'
100. Human embryonic stem cells are commonly derived from
A) Complete blastocyst B) Trophoblast
C) Inner cell mass (ICM) D) Cord blood cells
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